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    Sh3bgrl2 SH3 domain binding glutamic acid-rich protein like 2 [ Mus musculus (house mouse) ]

    Gene ID: 212531, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sh3bgrl2provided by MGI
    Official Full Name
    SH3 domain binding glutamic acid-rich protein like 2provided by MGI
    Primary source
    MGI:MGI:1915350
    See related
    Ensembl:ENSMUSG00000032261 AllianceGenome:MGI:1915350
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B930089I21; A930014C21Rik
    Summary
    Predicted to enable SH3 domain binding activity. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human SH3BGRL2 (SH3 domain binding glutamate rich protein like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in colon adult (RPKM 3.6), bladder adult (RPKM 2.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Sh3bgrl2 in Genome Data Viewer
    Location:
    9 E2; 9 45.49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (83430391..83482345)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (83548338..83600292)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene Leber congenital amaurosis 5 (human) Neighboring gene STARR-positive B cell enhancer mm9_chr9:83334629-83334930 Neighboring gene predicted gene 2087 Neighboring gene STARR-seq mESC enhancer starr_24788 Neighboring gene ribosomal protein S15A, pseudogene Neighboring gene STARR-seq mESC enhancer starr_24789 Neighboring gene STARR-seq mESC enhancer starr_24791 Neighboring gene predicted gene, 39384 Neighboring gene STARR-positive B cell enhancer mm9_chr9:83503556-83503857 Neighboring gene STARR-seq mESC enhancer starr_24792 Neighboring gene predicted gene, 36120 Neighboring gene predicted gene 2109

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SH3 domain-binding glutamic acid-rich-like protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172507.5NP_766095.1  SH3 domain-binding glutamic acid-rich-like protein 2

      See identical proteins and their annotated locations for NP_766095.1

      Status: PROVISIONAL

      Source sequence(s)
      AC113158, AC125106
      Consensus CDS
      CCDS40708.1
      UniProtKB/Swiss-Prot
      Q3TV64, Q8BG73
      UniProtKB/TrEMBL
      A0A087WS96, Q8C073
      Related
      ENSMUSP00000108841.4, ENSMUST00000113215.10
      Conserved Domains (1) summary
      cd03030
      Location:297
      GRX_SH3BGR; Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif. ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      83430391..83482345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)