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    Cox5b cytochrome c oxidase subunit 5B [ Mus musculus (house mouse) ]

    Gene ID: 12859, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cox5bprovided by MGI
    Official Full Name
    cytochrome c oxidase subunit 5Bprovided by MGI
    Primary source
    MGI:MGI:88475
    See related
    Ensembl:ENSMUSG00000061518 AllianceGenome:MGI:88475
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; heart; skeleton; and telencephalon. Orthologous to human COX5B (cytochrome c oxidase subunit 5B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 712.3), small intestine adult (RPKM 662.9) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Cox5b in Genome Data Viewer
    Location:
    1 B; 1 15.38 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (36730568..36732469)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (36691487..36693388)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C Neighboring gene family with sequence similarity 178, member B Neighboring gene STARR-seq mESC enhancer starr_00646 Neighboring gene RIKEN cDNA 4933424G06 gene Neighboring gene STARR-positive B cell enhancer ABC_E1539 Neighboring gene ARP1 actin-related protein 1B, centractin beta Neighboring gene predicted gene, 33533

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cytochrome c oxidase subunit 5B, mitochondrial
    Names
    cytochrome c oxidase polypeptide Vb
    cytochrome c oxidase subunit Vb
    NP_034072.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009942.2NP_034072.2  cytochrome c oxidase subunit 5B, mitochondrial

      See identical proteins and their annotated locations for NP_034072.2

      Status: VALIDATED

      Source sequence(s)
      AK135174, BU757937, CJ075429
      Consensus CDS
      CCDS14886.1
      UniProtKB/Swiss-Prot
      P19536
      UniProtKB/TrEMBL
      Q9D881
      Related
      ENSMUSP00000141554.2, ENSMUST00000193210.6
      Conserved Domains (1) summary
      pfam01215
      Location:8124
      COX5B; Cytochrome c oxidase subunit Vb

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      36730568..36732469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)