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    Lix1 limb and CNS expressed 1 [ Mus musculus (house mouse) ]

    Gene ID: 66643, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lix1provided by MGI
    Official Full Name
    limb and CNS expressed 1provided by MGI
    Primary source
    MGI:MGI:1913893
    See related
    Ensembl:ENSMUSG00000047786 AllianceGenome:MGI:1913893
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5730466L18Rik
    Summary
    Predicted to be involved in autophagosome maturation. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lateral plate mesoderm; and sensory organ. Orthologous to human LIX1 (limb and CNS expressed 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 15.1), cortex adult (RPKM 9.5) and 6 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Lix1 in Genome Data Viewer
    Location:
    17 A3.2; 17 9.77 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (17622948..17679649)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (17402686..17459387)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3184 Neighboring gene predicted gene, 36768 Neighboring gene STARR-positive B cell enhancer ABC_E7490 Neighboring gene RIO kinase 2 Neighboring gene STARR-seq mESC enhancer starr_41952 Neighboring gene predicted gene, 26873 Neighboring gene STARR-seq mESC enhancer starr_41957 Neighboring gene STARR-seq mESC enhancer starr_41959 Neighboring gene STARR-seq mESC enhancer starr_41960 Neighboring gene STARR-seq mESC enhancer starr_41961 Neighboring gene predicted gene, 41537 Neighboring gene proteasome (prosome, macropain) subunit, beta type 3 pseudogene Neighboring gene leucyl/cystinyl aminopeptidase Neighboring gene STARR-positive B cell enhancer ABC_E5575 Neighboring gene STARR-positive B cell enhancer ABC_E7491 Neighboring gene STARR-seq mESC enhancer starr_41962 Neighboring gene STARR-positive B cell enhancer ABC_E4194 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:17762259-17762524

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein limb expression 1 homolog
    Names
    limb expression 1 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025681.2NP_079957.2  protein limb expression 1 homolog

      See identical proteins and their annotated locations for NP_079957.2

      Status: VALIDATED

      Source sequence(s)
      BC049574, BC052700, BC063057
      Consensus CDS
      CCDS37456.1
      UniProtKB/Swiss-Prot
      Q6P566, Q8VHY1, Q9CYH4
      UniProtKB/TrEMBL
      A0A158RFU7, Q9CSQ3
      Related
      ENSMUSP00000111239.3, ENSMUST00000115576.3
      Conserved Domains (1) summary
      pfam14954
      Location:17258
      LIX1; Limb expression 1

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      17622948..17679649
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524797.5XP_006524860.1  protein limb expression 1 homolog isoform X1

      See identical proteins and their annotated locations for XP_006524860.1

      UniProtKB/TrEMBL
      Q3TSN5
      Related
      ENSMUSP00000156223.2, ENSMUST00000140134.2
      Conserved Domains (1) summary
      pfam14954
      Location:15131
      LIX1; Limb expression 1