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    Mrps27 mitochondrial ribosomal protein S27 [ Mus musculus (house mouse) ]

    Gene ID: 218506, updated on 27-Nov-2024

    Summary

    Official Symbol
    Mrps27provided by MGI
    Official Full Name
    mitochondrial ribosomal protein S27provided by MGI
    Primary source
    MGI:MGI:1919064
    See related
    Ensembl:ENSMUSG00000041632 AllianceGenome:MGI:1919064
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610028H14Rik
    Summary
    Predicted to enable mitochondrial ribosome binding activity; rRNA binding activity; and tRNA binding activity. Predicted to be involved in cell population proliferation and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; extraembryonic component; gonad; nervous system; and sensory organ. Orthologous to human MRPS27 (mitochondrial ribosomal protein S27). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in heart adult (RPKM 13.1), CNS E11.5 (RPKM 12.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mrps27 in Genome Data Viewer
    Location:
    13 D1; 13 52.83 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (99481275..99552070)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (99344767..99415562)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 366 Neighboring gene STARR-seq mESC enhancer starr_35452 Neighboring gene STARR-seq mESC enhancer starr_35453 Neighboring gene STARR-seq mESC enhancer starr_35456 Neighboring gene pentatricopeptide repeat domain 2 Neighboring gene STARR-positive B cell enhancer mm9_chr13:100123104-100123405 Neighboring gene RIKEN cDNA 6430562O15 gene Neighboring gene microtubule-associated protein 1B Neighboring gene STARR-seq mESC enhancer starr_35459 Neighboring gene predicted gene, 26559

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables mitochondrial ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mitochondrial ribosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables rRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables tRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables tRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell population proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of mitochondrial translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of mitochondrial translation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial small ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of mitochondrial small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein mS27
    Names
    28S ribosomal protein S27, mitochondrial
    MRP-S27
    S27mt

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173757.3NP_776118.2  small ribosomal subunit protein mS27

      See identical proteins and their annotated locations for NP_776118.2

      Status: VALIDATED

      Source sequence(s)
      AA461997, AK076008, AK087686
      Consensus CDS
      CCDS26722.1
      UniProtKB/Swiss-Prot
      E9QKZ5, Q8BK72
      Related
      ENSMUSP00000062326.6, ENSMUST00000052249.7
      Conserved Domains (2) summary
      sd00004
      Location:111135
      PPR; PPR repeat [structural motif]
      pfam10037
      Location:1412
      MRP-S27; Mitochondrial 28S ribosomal protein S27

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      99481275..99552070
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517602.1XP_006517665.1  small ribosomal subunit protein mS27 isoform X1

      Conserved Domains (2) summary
      sd00004
      Location:182212
      PPR; PPR repeat [structural motif]
      pfam10037
      Location:1453
      MRP-S27; Mitochondrial 28S ribosomal protein S27
    2. XM_017315495.2XP_017170984.1  small ribosomal subunit protein mS27 isoform X2

      Conserved Domains (2) summary
      sd00004
      Location:112142
      PPR; PPR repeat [structural motif]
      pfam10037
      Location:25383
      MRP-S27; Mitochondrial 28S ribosomal protein S27
    3. XM_017315496.2XP_017170985.1  small ribosomal subunit protein mS27 isoform X3

      Conserved Domains (2) summary
      sd00004
      Location:4165
      PPR; PPR repeat [structural motif]
      pfam10037
      Location:25342
      MRP-S27; Mitochondrial 28S ribosomal protein S27
    4. XM_036158019.1XP_036013912.1  small ribosomal subunit protein mS27 isoform X4

      UniProtKB/TrEMBL
      Q80ZI4
      Conserved Domains (2) summary
      sd00004
      Location:3363
      PPR; PPR repeat [structural motif]
      pfam10037
      Location:25304
      MRP-S27; Mitochondrial 28S ribosomal protein S27