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    LPP LIM domain containing preferred translocation partner in lipoma [ Homo sapiens (human) ]

    Gene ID: 4026, updated on 27-Nov-2024

    Summary

    Official Symbol
    LPPprovided by HGNC
    Official Full Name
    LIM domain containing preferred translocation partner in lipomaprovided by HGNC
    Primary source
    HGNC:HGNC:6679
    See related
    Ensembl:ENSG00000145012 MIM:600700; AllianceGenome:HGNC:6679
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
    Expression
    Ubiquitous expression in endometrium (RPKM 14.7), esophagus (RPKM 14.3) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See LPP in Genome Data Viewer
    Location:
    3q27.3-q28
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (188153021..188890671)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (190970544..191707297)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (187870809..188608460)

    Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20974 Neighboring gene Sharpr-MPRA regulatory region 2895 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:187707584-187708117 Neighboring gene uncharacterized LOC107986166 Neighboring gene long intergenic non-protein coding RNA 1991 Neighboring gene Sharpr-MPRA regulatory region 1686 Neighboring gene Sharpr-MPRA regulatory region 10187 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:187769983-187770955 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr3:187870480-187871380 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14995 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:187873180-187874078 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr3:187882030-187883229 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:187897095-187897707 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 20975 Neighboring gene LPP antisense RNA 2 Neighboring gene uncharacterized LOC401105 Neighboring gene Sharpr-MPRA regulatory region 910 Neighboring gene uncharacterized LOC124906316 Neighboring gene LPP antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:188353620-188354172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr3:188354173-188354724 Neighboring gene microRNA 28 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 14996 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:188600153-188600654 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:188600655-188601154 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr3:188618060-188619259 Neighboring gene Sharpr-MPRA regulatory region 14211 Neighboring gene NANOG hESC enhancer GRCh37_chr3:188655166-188655667 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr3:188655787-188656288 Neighboring gene Sharpr-MPRA regulatory region 11355 Neighboring gene NANOG hESC enhancer GRCh37_chr3:188674939-188675473 Neighboring gene TPRG1 antisense RNA 1 Neighboring gene ENOPH1 pseudogene 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
    EBI GWAS Catalog
    A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.
    EBI GWAS Catalog
    Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.
    EBI GWAS Catalog
    Familial young-onset diabetes, pre-diabetes and cardiovascular disease are associated with genetic variants of DACH1 in Chinese.
    EBI GWAS Catalog
    Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
    EBI GWAS Catalog
    Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.
    EBI GWAS Catalog
    Genome-wide Association Study Identifies Five Susceptibility Loci for Follicular Lymphoma outside the HLA Region.
    EBI GWAS Catalog
    Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population.
    EBI GWAS Catalog
    Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations
    EBI GWAS Catalog
    Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
    EBI GWAS Catalog
    Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.
    EBI GWAS Catalog
    Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.
    EBI GWAS Catalog
    Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization.
    EBI GWAS Catalog
    Multiple common variants for celiac disease influencing immune gene expression.
    EBI GWAS Catalog
    Newly identified genetic risk variants for celiac disease related to the immune response.
    EBI GWAS Catalog
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    EBI GWAS Catalog
    Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.
    EBI GWAS Catalog
    White matter integrity as an intermediate phenotype: exploratory genome-wide association analysis in individuals at high risk of bipolar disorder.
    EBI GWAS Catalog

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of LIM domain containing preferred translocation partner in lipoma (LPP) by siRNA enhances HIV-1 replication in CD4+/CCR5+/CXCR4+ TZM-bl HeLa cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ30652, FLJ41512, DKFZp779O0231

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in focal adhesion HDA PubMed 
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in stress fiber IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    lipoma-preferred partner
    Names
    LIM protein
    lipoma preferred partner

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_016932.2 RefSeqGene

      Range
      5283..741797
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001167671.3NP_001161143.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    2. NM_001167672.3NP_001161144.1  lipoma-preferred partner isoform b

      Status: REVIEWED

      Source sequence(s)
      AC009319, AI126032, AK304035, AW301088, CD697098, KF510228
      UniProtKB/TrEMBL
      B7Z8W0
      Conserved Domains (3) summary
      cd09350
      Location:269322
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:329381
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cl02475
      Location:389454
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    3. NM_001375455.1NP_001362384.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    4. NM_001375456.1NP_001362385.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    5. NM_001375457.1NP_001362386.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    6. NM_001375458.1NP_001362387.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Related
      ENSP00000392667.2, ENST00000414139.6
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    7. NM_001375459.1NP_001362388.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    8. NM_001375460.1NP_001362389.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    9. NM_001375461.1NP_001362390.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    10. NM_001375462.1NP_001362391.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Related
      ENSP00000478901.1, ENST00000617246.5
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    11. NM_001375463.1NP_001362392.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    12. NM_001375464.1NP_001362393.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    13. NM_001375465.1NP_001362394.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Related
      ENSP00000405138.2, ENST00000420410.6
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    14. NM_001387663.1NP_001374592.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    15. NM_001387664.1NP_001374593.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    16. NM_001387665.1NP_001374594.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    17. NM_001387666.1NP_001374595.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    18. NM_001387667.1NP_001374596.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    19. NM_001387668.1NP_001374597.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    20. NM_001387669.1NP_001374598.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    21. NM_001387670.1NP_001374599.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    22. NM_001387671.1NP_001374600.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    23. NM_001387672.1NP_001374601.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    24. NM_001387673.1NP_001374602.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    25. NM_001387674.1NP_001374603.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    26. NM_001387675.1NP_001374604.1  lipoma-preferred partner isoform c

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC055711, AC063932, KF510228
      UniProtKB/TrEMBL
      B7Z871
      Conserved Domains (4) summary
      cd09350
      Location:253306
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:313365
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PRK14086
      Location:28217
      dnaA; chromosomal replication initiator protein DnaA
      cl02475
      Location:373438
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    27. NM_001387676.1NP_001374605.1  lipoma-preferred partner isoform c

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC055711, AC063932, KF510228
      UniProtKB/TrEMBL
      B7Z871
      Conserved Domains (4) summary
      cd09350
      Location:253306
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:313365
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PRK14086
      Location:28217
      dnaA; chromosomal replication initiator protein DnaA
      cl02475
      Location:373438
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    28. NM_001387677.1NP_001374606.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    29. NM_001387678.1NP_001374607.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    30. NM_001387679.1NP_001374608.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    31. NM_001387680.1NP_001374609.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    32. NM_001387681.1NP_001374610.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    33. NM_001387682.1NP_001374611.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226, AC117507
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    34. NM_001387683.1NP_001374612.1  lipoma-preferred partner isoform d

      Status: REVIEWED

      Source sequence(s)
      AC022498, AC063932, AC069226
      UniProtKB/TrEMBL
      C9JUT4
      Conserved Domains (2) summary
      PRK14086
      Location:191370
      dnaA; chromosomal replication initiator protein DnaA
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunit gamma/tau
    35. NM_005578.5NP_005569.1  lipoma-preferred partner isoform a

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228
      Consensus CDS
      CCDS3291.1
      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Related
      ENSP00000482617.2, ENST00000618621.5
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional

    RNA

    1. NR_164692.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC009319, AC022498, AC055711, AC063932, AC069226, AC117507, KF510228

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

      Range
      188153021..188890671
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047448103.1XP_047304059.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    2. XM_047448109.1XP_047304065.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    3. XM_047448102.1XP_047304058.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    4. XM_047448112.1XP_047304068.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    5. XM_047448107.1XP_047304063.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    6. XM_047448115.1XP_047304071.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    7. XM_047448105.1XP_047304061.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    8. XM_047448097.1XP_047304053.1  lipoma-preferred partner isoform X1

    9. XM_047448099.1XP_047304055.1  lipoma-preferred partner isoform X4

    10. XM_047448104.1XP_047304060.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    11. XM_047448108.1XP_047304064.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    12. XM_047448114.1XP_047304070.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    13. XM_047448106.1XP_047304062.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    14. XM_047448113.1XP_047304069.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    15. XM_047448111.1XP_047304067.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    16. XM_047448101.1XP_047304057.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    17. XM_047448110.1XP_047304066.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    18. XM_047448098.1XP_047304054.1  lipoma-preferred partner isoform X2

    19. XM_017006378.2XP_016861867.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:416469
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:476528
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:536601
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      PHA03247
      Location:19388
      PHA03247; large tegument protein UL36; Provisional
    20. XM_047448116.1XP_047304072.1  lipoma-preferred partner isoform X7

    21. XM_017006381.1XP_016861870.1  lipoma-preferred partner isoform X8

      UniProtKB/TrEMBL
      C9JUT4
      Related
      ENSP00000393602.1, ENST00000448637.5
      Conserved Domains (2) summary
      PRK14086
      Location:191380
      dnaA; chromosomal replication initiation protein; Provisional
      PRK14971
      Location:141219
      PRK14971; DNA polymerase III subunits gamma and tau; Provisional
    22. XM_011512823.3XP_011511125.1  lipoma-preferred partner isoform X3

      UniProtKB/TrEMBL
      B7ZLW0
      Conserved Domains (4) summary
      cd09350
      Location:441494
      LIM1_TRIP6; The first LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09356
      Location:501553
      LIM2_TRIP6; The second LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cd09436
      Location:561626
      LIM3_TRIP6; The third LIM domain of Thyroid receptor-interacting protein 6 (TRIP6)
      cl23807
      Location:229316
      WWbp; WW-domain ligand protein
    23. XM_047448100.1XP_047304056.1  lipoma-preferred partner isoform X5

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060927.1 Alternate T2T-CHM13v2.0

      Range
      190970544..191707297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054346494.1XP_054202469.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    2. XM_054346500.1XP_054202475.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    3. XM_054346493.1XP_054202468.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    4. XM_054346502.1XP_054202477.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    5. XM_054346498.1XP_054202473.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    6. XM_054346505.1XP_054202480.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    7. XM_054346496.1XP_054202471.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    8. XM_054346487.1XP_054202462.1  lipoma-preferred partner isoform X1

    9. XM_054346490.1XP_054202465.1  lipoma-preferred partner isoform X4

    10. XM_054346495.1XP_054202470.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    11. XM_054346499.1XP_054202474.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    12. XM_054346504.1XP_054202479.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    13. XM_054346497.1XP_054202472.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    14. XM_054346503.1XP_054202478.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    15. XM_054346501.1XP_054202476.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    16. XM_054346492.1XP_054202467.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    17. XM_054346488.1XP_054202463.1  lipoma-preferred partner isoform X2

    18. XM_054346507.1XP_054202482.1  lipoma-preferred partner isoform X6

      UniProtKB/Swiss-Prot
      A1L4L6, D3DNV6, Q8NFX5, Q93052
    19. XM_054346506.1XP_054202481.1  lipoma-preferred partner isoform X7

    20. XM_054346508.1XP_054202483.1  lipoma-preferred partner isoform X8

    21. XM_054346489.1XP_054202464.1  lipoma-preferred partner isoform X3

    22. XM_054346491.1XP_054202466.1  lipoma-preferred partner isoform X5