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    ADAM3B ADAM metallopeptidase domain 3B (pseudogene) [ Homo sapiens (human) ]

    Gene ID: 1596, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ADAM3Bprovided by HGNC
    Official Full Name
    ADAM metallopeptidase domain 3B (pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:210
    See related
    Ensembl:ENSG00000260089 AllianceGenome:HGNC:210
    Gene type
    pseudo
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CYRN2
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    Genomic context

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    See ADAM3B in Genome Data Viewer
    Location:
    16q12.1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (49517646..49518585, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (55315309..55316249, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (49551557..49552496, complement)

    Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105371244 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49407168-49407898 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49407899-49408629 Neighboring gene chromosome 16 open reading frame 78 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49464652-49465152 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49465153-49465653 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49475185-49476132 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49477189-49477690 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49498687-49499188 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7461 Neighboring gene long intergenic non-protein coding RNA 2179 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49526437-49527060 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49527061-49527682 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10805 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10804 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49557435-49557934 Neighboring gene zinc finger protein 423 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49561586-49562584 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49572197-49572697 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49572734-49573234 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49582132-49582944 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49582945-49583756 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49591427-49592314 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:49602152-49602652 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:49602653-49603153 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49630850-49631370 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49649657-49650157 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49649156-49649656 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49651175-49651675 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr16:49681934-49683133 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49695163-49695664 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49695665-49696164 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49696971-49697505 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49697506-49698039 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:49714232-49715152 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49729865-49730546 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49730547-49731228 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49731229-49731910 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49731911-49732592 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49732593-49733274 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49733957-49734638 Neighboring gene VISTA enhancer hs625 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49738731-49739411 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49746094-49746661 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49746662-49747228 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49753579-49754080 Neighboring gene mitochondrial ribosomal protein S21 pseudogene 7 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49778329-49778910 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:49780200-49780700 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49787863-49788521 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:49788522-49789180 Neighboring gene mitochondrial ribosomal protein S21 pseudogene 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assignment of the germ cell cyritestin gene 2 (CYRN2) to human chromosome 16q12.1 by fluorescence in situ hybridization to 5-azacytidine induced, partially decondensed chromosomes. Koehler MR, et al. Cytogenet Cell Genet, 1997. PMID 9284909
    2. Evolutionary divergence and functions of the ADAM and ADAMTS gene families. Brocker CN, et al. Hum Genomics, 2009 Oct. PMID 19951893, Free PMC Article
    3. Human cyritestin genes (CYRN1 and CYRN2) are non-functional. Grzmil P, et al. Biochem J, 2001 Jul 15. PMID 11439107, Free PMC Article
    4. The gene for the human tMDC I sperm surface protein is non-functional: implications for its proposed role in mammalian sperm-egg recognition. Frayne J, et al. Biochem J, 1998 Aug 15. PMID 9693117, Free PMC Article
    5. Molecular cloning, chromosomal localization, and expression analysis of CYRN1 and CYRN2, two human genes coding for cyritestin, a sperm protein involved in gamete interaction. Adham IM, et al. DNA Cell Biol, 1998 Feb. PMID 9502432

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    General gene information

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    Other Names

    • ADAM metallopeptidase domain 3B (cyritestin 2)
    • ADAM metallopeptidase domain 3B (non-functional)
    • a disintegrin and metalloproteinase domain 3b (cyritestin 2)
    • cyritestin 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_144553.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC007861, AF334867
      Related
      ENST00000569937.2

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

      Range
      49517646..49518585 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060940.1 Alternate T2T-CHM13v2.0

      Range
      55315309..55316249 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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