Ddit4l DNA-damage-inducible transcript 4-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ddit4lprovided by RGD
Official Full Name: DNA-damage-inducible transcript 4-likeprovided by RGD
Primary source: RGD:2322961
See related: EnsemblRapid:ENSRNOG00000010047 AllianceGenome:RGD:2322961
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in negative regulation of signal transduction. Predicted to be located in cytoplasm. Orthologous to human DDIT4L (DNA damage inducible transcript 4 like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 716.0), Heart (RPKM 122.6) and 2 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q43

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (228800831..228804478)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (226128273..226131044)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (242882219..242885088)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in negative regulation of signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: DNA damage-inducible transcript 4-like protein

Names: DNA-damage-inducible transcript 4-like protein-like; soleus muscle atrophied after hindlimb suspension protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001389274.1 → NP_001376203.1 DNA damage-inducible transcript 4-like protein

Status: VALIDATED

Source sequence(s)

JAXUCZ010000002

UniProtKB/Swiss-Prot

Q8VD50

UniProtKB/TrEMBL

A6HW05

Related

ENSRNOP00000109266.1, ENSRNOT00000131224.1

Conserved Domains (1) summary

pfam07809
Location:65 → 183

RTP801_C; RTP801 C-terminal region