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    Tmem184b transmembrane protein 184B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362959, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tmem184bprovided by RGD
    Official Full Name
    transmembrane protein 184Bprovided by RGD
    Primary source
    RGD:1306591
    See related
    EnsemblRapid:ENSRNOG00000022802 AllianceGenome:RGD:1306591
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306591
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be active in membrane. Orthologous to human TMEM184B (transmembrane protein 184B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 98.5), Heart (RPKM 95.9) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tmem184b in Genome Data Viewer
    Location:
    7q34
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (112805512..112848398, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (110925092..110967975, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (120593336..120636592, complement)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group VI Neighboring gene MAF bZIP transcription factor F Neighboring gene casein kinase 1, epsilon Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 184B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173370.1 → NP_001166841.1  transmembrane protein 184B

      See identical proteins and their annotated locations for NP_001166841.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A6HSR6, G3V924, Q499S3
      Related
      ENSRNOP00000034031.2, ENSRNOT00000031117.6
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 317
      Solute_trans_a; Organic solute transporter Ostalpha

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      112805512..112848398 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242013.5 → XP_006242075.1  transmembrane protein 184B isoform X1

      See identical proteins and their annotated locations for XP_006242075.1

      UniProtKB/TrEMBL
      A0A0G2K0C2, Q499S3
      Related
      ENSRNOP00000071385.1, ENSRNOT00000091317.3
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 317
      Solute_trans_a; Organic solute transporter Ostalpha

    2. XM_017594986.3 → XP_017450475.1  transmembrane protein 184B isoform X1

      UniProtKB/TrEMBL
      A0A0G2K0C2, Q499S3
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 317
      Solute_trans_a; Organic solute transporter Ostalpha

    3. XM_063263923.1 → XP_063119993.1  transmembrane protein 184B isoform X2

      UniProtKB/TrEMBL
      A6HSR6, G3V924, Q499S3

    4. XM_006242014.5 → XP_006242076.1  transmembrane protein 184B isoform X1

      See identical proteins and their annotated locations for XP_006242076.1

      UniProtKB/TrEMBL
      A0A0G2K0C2, Q499S3
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 317
      Solute_trans_a; Organic solute transporter Ostalpha

    5. XM_063263922.1 → XP_063119992.1  transmembrane protein 184B isoform X1

      UniProtKB/TrEMBL
      A0A0G2K0C2, Q499S3

    6. XM_039079585.2 → XP_038935513.1  transmembrane protein 184B isoform X1

      UniProtKB/TrEMBL
      A0A0G2K0C2, Q499S3
      Conserved Domains (1) summary
      pfam03619
      Location:46 → 317
      Solute_trans_a; Organic solute transporter Ostalpha
    Nucleotide Protein Strain
    Heading Accession and Version

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