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    Armc3 armadillo repeat containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100361506, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Armc3provided by RGD
    Official Full Name
    armadillo repeat containing 3provided by RGD
    Primary source
    RGD:2319961
    See related
    EnsemblRapid:ENSRNOG00000016716 AllianceGenome:RGD:2319961
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in flagellated sperm motility; ribophagy; and spermatid development. Orthologous to human ARMC3 (armadillo repeat containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 125.3), Kidney (RPKM 23.3) and 1 other tissue See more
    Orthologs
    human mouse all
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    Genomic context

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    See Armc3 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (86722436..86825899)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (81814087..81917534)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (85895841..86009403)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120097847 Neighboring gene phosphatidylinositol-5-phosphate 4-kinase type 2 alpha Neighboring gene hypothetical LOC100361451 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene PICALM interacting mitotic regulator like 1 Neighboring gene uncharacterized LOC102556079 Neighboring gene uncharacterized LOC134482617 Neighboring gene methionine sulfoxide reductase B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Gene and alternative splicing annotation with AIR. Florea L, et al. Genome Res, 2005 Jan. PMID 15632090, Free PMC Article
    2. Large-scale proteomics and phosphoproteomics of urinary exosomes. Gonzales PA, et al. J Am Soc Nephrol, 2009 Feb. PMID 19056867, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in flagellated sperm motility ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribophagy ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in spermatid development ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    armadillo repeat-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001287020.1 → NP_001273949.1  armadillo repeat-containing protein 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      M0R914
      Conserved Domains (5) summary
      cd00020
      Location:145 → 259
      ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
      pfam13646
      Location:152 → 258
      HEAT_2; HEAT repeats
      pfam14381
      Location:712 → 850
      EDR1; Ethylene-responsive protein kinase Le-CTR1
      sd00044
      Location:316 → 342
      HEAT; HEAT repeat [structural motif]
      sd00043
      Location:22 → 52
      ARM; armadillo repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      86722436..86825899
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017600429.3 → XP_017455918.1  armadillo repeat-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      M0R914
      Related
      ENSRNOP00000103893.1, ENSRNOT00000171634.1

    2. XM_017600428.3 → XP_017455917.1  armadillo repeat-containing protein 3 isoform X1

      UniProtKB/TrEMBL
      M0R914
      Related
      ENSRNOP00000103410.1, ENSRNOT00000141115.1

    3. XM_017600430.3 → XP_017455919.1  armadillo repeat-containing protein 3 isoform X2

      UniProtKB/TrEMBL
      M0R914

    4. XM_017600431.3 → XP_017455920.1  armadillo repeat-containing protein 3 isoform X4

      UniProtKB/TrEMBL
      A6JM99

    5. XM_063276004.1 → XP_063132074.1  armadillo repeat-containing protein 3 isoform X3

      UniProtKB/TrEMBL
      M0R914

    6. XM_039095275.2 → XP_038951203.1  armadillo repeat-containing protein 3 isoform X5

      UniProtKB/TrEMBL
      A6JM99
      Conserved Domains (5) summary
      smart00185
      Location:469 → 504
      ARM; Armadillo/beta-catenin-like repeats
      PLN03200
      Location:149 → 215
      PLN03200; cellulose synthase-interactive protein; Provisional
      COG5064
      Location:11 → 177
      SRP1; Karyopherin (importin) alpha [Intracellular trafficking and secretion]
      sd00043
      Location:60 → 96
      ARM; armadillo repeat [structural motif]
      pfam00514
      Location:143 → 178
      Arm; Armadillo/beta-catenin-like repeat
    Nucleotide Protein Strain
    Heading Accession and Version

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