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    lrhA DNA-binding transcriptional dual regulator LrhA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946769, updated on 17-Dec-2024

    Summary

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    Official Symbol
    lrhA
    Official Full Name
    DNA-binding transcriptional dual regulator LrhA
    Primary source
    ECOCYC:EG12123
    Locus tag
    b2289
    See related
    ASAP:ABE-0007555
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2283; genR
    Summary
    LysR family. [More information is available at EcoGene: EG12123]. LrhA, "LysR homologue A," regulates the transcription of genes involved in the synthesis of type 1 fimbriae . [More information is available at EcoCyc: EG12123].
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    Genomic context

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    Sequence:
    NC_000913.3 (2405703..2406641, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene NADH:quinone oxidoreductase subunit B Neighboring gene NADH:quinone oxidoreductase subunit A Neighboring gene glutamate--pyruvate aminotransferase AlaA Neighboring gene dCMP phosphohydrolase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characteristics of the LrhA subfamily of transcriptional regulators from Sinorhizobium meliloti. Qi M, et al. Acta Biochim Biophys Sin (Shanghai), 2008 Feb. PMID 18235979
    2. The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants. Harris SJ, et al. Mol Microbiol, 1998 May. PMID 9643539
    3. The Erwinia chrysanthemi pecT gene regulates pectinase gene expression. Surgey N, et al. J Bacteriol, 1996 Mar. PMID 8626286, Free PMC Article
    4. Mutations upregulating the flhDC operon of Escherichia coli K-12. Lee C, et al. J Microbiol, 2013 Feb. PMID 23456724
    5. LrhA as a new transcriptional key regulator of flagella, motility and chemotaxis genes in Escherichia coli. Lehnen D, et al. Mol Microbiol, 2002 Jul. PMID 12123461

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional dual regulator LrhA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2405703..2406641 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416792.1 DNA-binding transcriptional dual regulator LrhA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416792.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376M4Z4, A0A5B9AL51
      Conserved Domains (1) summary
      PRK15092
      Location:1 → 310
      PRK15092; DNA-binding transcriptional repressor LrhA; Provisional
    Nucleotide Protein
    Heading Accession and Version

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