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    sohB S49 peptidase family protein [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 945858, updated on 3-Dec-2024

    Summary

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    Official Symbol
    sohB
    Official Full Name
    S49 peptidase family protein
    Primary source
    ECOCYC:EG10956
    Locus tag
    b1272
    See related
    ASAP:ABE-0004267
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1266
    Summary
    SohB is homologous to inner membrane protease IV, which digests cleaved signal peptides. [More information is available at EcoGene: EG10956]. SohB might be a periplasmic protease, based on sequence analysis and the genetic interaction between sohB and htrA . [More information is available at EcoCyc: EG10956].
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    Genomic context

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    Sequence:
    NC_000913.3 (1329332..1330381)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 23S rRNA pseudouridine(2605) synthase Neighboring gene cobinamide/cobalamin adenosyltransferase Neighboring gene putative oxidoreductase Neighboring gene protein YciN Neighboring gene DNA topoisomerase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the Escherichia coli sohB gene, a multicopy suppressor of the HtrA (DegP) null phenotype. Baird L, et al. J Bacteriol, 1991 Sep. PMID 1885549, Free PMC Article
    2. Complete nucleotide sequence of the topA gene encoding Escherichia coli DNA topoisomerase I. Tse-Dinh YC, et al. J Mol Biol, 1986 Oct 5. PMID 3029379
    3. RpoS-dependent regulation of genes expressed at late stationary phase in Escherichia coli. Talukder AA, et al. FEBS Lett, 1996 May 20. PMID 8647276
    4. Membranome: a database for proteome-wide analysis of single-pass membrane proteins. Lomize AL, et al. Nucleic Acids Res, 2017 Jan 4. PMID 27510400, Free PMC Article
    5. Comparison of SDS- and methanol-assisted protein solubilization and digestion methods for Escherichia coli membrane proteome analysis by 2-D LC-MS/MS. Zhang N, et al. Proteomics, 2007 Feb. PMID 17309111

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type peptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within proteolysis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    S49 peptidase family protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1329332..1330381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_415788.1 S49 peptidase family protein [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_415788.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376MWD7
      Conserved Domains (1) summary
      PRK11778
      Location:3 → 341
      PRK11778; putative inner membrane peptidase; Provisional
    Nucleotide Protein
    Heading Accession and Version

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