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    xapR DNA-binding transcriptional activator XapR [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946862, updated on 17-Dec-2024

    Summary

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    Official Symbol
    xapR
    Official Full Name
    DNA-binding transcriptional activator XapR
    Primary source
    ECOCYC:EG11146
    Locus tag
    b2405
    See related
    ASAP:ABE-0007922
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2399; pndR; pRndR; yfeB
    Summary
    LysR family. [More information is available at EcoGene: EG11146]. The XapR protein belongs to the LysR family of transcriptional regulators. [More information is available at EcoCyc: EG11146].
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    Genomic context

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    Sequence:
    NC_000913.3 (2521593..2522477, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Val Neighboring gene tRNA-Lys Neighboring gene xanthosine:H(+) symporter XapB Neighboring gene xanthosine phosphorylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Isolation and characterization of mutations in the Escherichia coli regulatory protein XapR. Jørgensen C, et al. J Bacteriol, 1999 Jul. PMID 10400599, Free PMC Article
    2. A second purine nucleoside phosphorylase in Escherichia coli K-12. I. Xanthosine phosphorylase regulatory mutants isolated as secondary-site revertants of a deoD mutant. Buxton RS, et al. Mol Gen Genet, 1980. PMID 7007808
    3. Group II intron protein localization and insertion sites are affected by polyphosphate. Zhao J, et al. PLoS Biol, 2008 Jun 24. PMID 18593213, Free PMC Article
    4. Precise mapping and comparison of two evolutionarily related regions of the Escherichia coli K-12 chromosome. Evolution of valU and lysT from an ancestral tRNA operon. Brun YV, et al. J Mol Biol, 1990 Aug 20. PMID 2201776
    5. Identification and characterization of genes (xapA, xapB, and xapR) involved in xanthosine catabolism in Escherichia coli. Seeger C, et al. J Bacteriol, 1995 Oct. PMID 7559336, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-DNA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DNA-binding transcriptional activator XapR

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      2521593..2522477 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416900.1 DNA-binding transcriptional activator XapR [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416900.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376SAV2
      Conserved Domains (1) summary
      PRK09986
      Location:1 → 292
      PRK09986; LysR family transcriptional regulator
    Nucleotide Protein
    Heading Accession and Version

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