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    rsmD 16S rRNA m(2)G966 methyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947977, updated on 3-Dec-2024

    Summary

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    Official Symbol
    rsmD
    Official Full Name
    16S rRNA m(2)G966 methyltransferase
    Primary source
    ECOCYC:EG10343
    Locus tag
    b3465
    See related
    ASAP:ABE-0011321
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3449; yhhF
    Summary
    A yhhF mutation confers a slight growth disadvantage. [More information is available at EcoGene: EG10343]. RsmD is the methyltransferase responsible for methylation of 16S rRNA at the N2 postion of the G966 nucleotide . [More information is available at EcoCyc: EG10343].
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    Genomic context

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    Sequence:
    NC_000913.3 (3604393..3604989)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene cell division protein FtsX Neighboring gene cell division protein FtsE Neighboring gene signal recognition particle receptor Neighboring gene DUF1145 domain-containing protein YhhL Neighboring gene DUF2500 domain-containing protein YhhM Neighboring gene PF07947 family protein YhhN

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A new cell division operon in Escherichia coli. Gill DR, et al. Mol Gen Genet, 1986 Oct. PMID 3025556
    2. Role of 16S ribosomal RNA methylations in translation initiation in Escherichia coli. Das G, et al. EMBO J, 2008 Mar 19. PMID 18288206, Free PMC Article
    3. A paradigm for local conformational control of function in the ribosome: binding of ribosomal protein S19 to Escherichia coli 16S rRNA in the presence of S7 is required for methylation of m2G966 and blocks methylation of m5C967 by their respective methyltransferases. Weitzmann C, et al. Nucleic Acids Res, 1991 Dec. PMID 1766869, Free PMC Article
    4. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article
    5. Interaction network containing conserved and essential protein complexes in Escherichia coli. Butland G, et al. Nature, 2005 Feb 3. PMID 15690043

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 16S rRNA (guanine(966)-N(2))-methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 16S rRNA (guanine(966)-N(2))-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within rRNA base methylation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    16S rRNA m(2)G966 methyltransferase
    NP_417922.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3604393..3604989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417922.1 16S rRNA m(2)G966 methyltransferase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417922.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A376FVM6
      Conserved Domains (1) summary
      PRK10909
      Location:1 → 198
      rsmD; 16S rRNA m(2)G966-methyltransferase; Provisional
    Nucleotide Protein
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