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    Cstf2t cleavage stimulation factor, 3' pre-RNA subunit 2, tau [ Mus musculus (house mouse) ]

    Gene ID: 83410, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cstf2tprovided by MGI
    Official Full Name
    cleavage stimulation factor, 3' pre-RNA subunit 2, tauprovided by MGI
    Primary source
    MGI:MGI:1932622
    See related
    Ensembl:ENSMUSG00000053536 AllianceGenome:MGI:1932622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    64kDa; tCstF-64; tauCstF-64
    Summary
    Enables RNA binding activity. Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be located in nucleoplasm. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in brain and spinal cord. Orthologous to human CSTF2T (cleavage stimulation factor subunit 2 tau variant). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See Cstf2t in Genome Data Viewer
    Location:
    19 C1; 19 25.94 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (31060241..31063992)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (31082841..31086592)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene protein kinase, cGMP-dependent, type I Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E1 pseudogene Neighboring gene ubiquitin-like 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_45914 Neighboring gene STARR-positive B cell enhancer ABC_E7644 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:31157349-31157532 Neighboring gene STARR-seq mESC enhancer starr_45917 Neighboring gene STARR-seq mESC enhancer starr_45919 Neighboring gene STARR-seq mESC enhancer starr_45920 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene RIKEN cDNA 8430431K14 gene

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA 3'-end processing TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mRNA cleavage and polyadenylation specificity factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cleavage stimulation factor subunit 2 tau variant
    Names
    CF-1 64 kDa subunit, tau
    CSTF 64 kDa subunit, tau
    cleavage stimulation factor 64 kDa subunit, tau
    cleavage stimulation factor subunit 2 tau
    cleavage stimulation factor, 3' pre-RNA subunit 2, 64 kDa, tau

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031249.2NP_112539.2  cleavage stimulation factor subunit 2 tau variant

      See identical proteins and their annotated locations for NP_112539.2

      Status: VALIDATED

      Source sequence(s)
      AK082910, BY637182, CJ182579
      Consensus CDS
      CCDS37958.1
      UniProtKB/Swiss-Prot
      Q6A016, Q8BHH7, Q8C3W7, Q8C7E9, Q8R2Y1, Q9EPU3
      Related
      ENSMUSP00000093831.4, ENSMUST00000066039.8
      Conserved Domains (4) summary
      COG0724
      Location:16109
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12671
      Location:1892
      RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
      pfam14304
      Location:588628
      CSTF_C; Transcription termination and cleavage factor C-terminal
      pfam14327
      Location:113191
      CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      31060241..31063992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)