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    Speg SPEG complex locus [ Mus musculus (house mouse) ]

    Gene ID: 11790, updated on 9-Dec-2024

    Summary

    Official Symbol
    Spegprovided by MGI
    Official Full Name
    SPEG complex locusprovided by MGI
    Primary source
    MGI:MGI:109282
    See related
    Ensembl:ENSMUSG00000026207 AllianceGenome:MGI:109282
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BPEG; Apeg1; APEG-1; SPEGbeta; SPEGalpha; mKIAA1297; D1Bwg1450e
    Summary
    This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants that encode different protein isoforms have been defined. [provided by RefSeq, Mar 2010]
    Expression
    Broad expression in heart adult (RPKM 14.9), cortex adult (RPKM 9.1) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Speg in Genome Data Viewer
    Location:
    1 C4; 1 38.88 cM
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (75351931..75408964)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (75375297..75432320)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene aspartyl aminopeptidase Neighboring gene desmin upstream regulatory region Neighboring gene predicted gene 15179 Neighboring gene desmin Neighboring gene STARR-seq mESC enhancer starr_01359 Neighboring gene GDP-mannose pyrophosphorylase A Neighboring gene predicted gene, 53564 Neighboring gene acid-sensing ion channel family member 4 Neighboring gene predicted gene, 32506

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (5)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 3-phosphoinositide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables Rho-dependent protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables eukaryotic translation initiation factor 2alpha kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AS121 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AT120 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2AXS139 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS14 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H2BS36 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S10 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S28 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3S57 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T11 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T3 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T45 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H3T6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables histone H4S1 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ribosomal protein S6 kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    striated muscle-specific serine/threonine-protein kinase
    Names
    aortic preferentially expressed gene 1
    aortic preferentially expressed protein 1
    NP_001078839.1
    NP_001078840.1
    NP_001166948.1
    NP_031489.4
    XP_006496464.1
    XP_006496465.1
    XP_006496466.1
    XP_006496467.1
    XP_011236945.1
    XP_011236946.1
    XP_011236947.1
    XP_011236948.1
    XP_011236949.1
    XP_011236950.1
    XP_011236951.1
    XP_011236953.1
    XP_017167765.1
    XP_017177843.1
    XP_017177864.1
    XP_030099133.1
    XP_030099208.1
    XP_030099228.1
    XP_030099250.1
    XP_030099262.1
    XP_030099307.1
    XP_030099336.1
    XP_030099354.1
    XP_030099372.1
    XP_030099381.1
    XP_036010913.1
    XP_036011038.1
    XP_036011068.1
    XP_036011090.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085370.2NP_001078839.1  striated muscle-specific serine/threonine-protein kinase isoform 2

      See identical proteins and their annotated locations for NP_001078839.1

      Status: VALIDATED

      Source sequence(s)
      AC114651
      UniProtKB/TrEMBL
      A0A087WSE3
      Related
      ENSMUSP00000141009.2, ENSMUST00000137868.8
      Conserved Domains (8) summary
      PHA03247
      Location:12061610
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14901812
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:19462032
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8681124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:22222478
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755844
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:243328
      Ig; Immunoglobulin domain
    2. NM_001085371.2NP_001078840.1  striated muscle-specific serine/threonine-protein kinase isoform 3

      See identical proteins and their annotated locations for NP_001078840.1

      Status: VALIDATED

      Source sequence(s)
      AC114651
      Consensus CDS
      CCDS48292.1
      UniProtKB/Swiss-Prot
      Q62407
      Related
      ENSMUSP00000109220.2, ENSMUST00000113590.8
      Conserved Domains (4) summary
      smart00408
      Location:781848
      IGc2; Immunoglobulin C-2 Type
      pfam07679
      Location:621710
      I-set; Immunoglobulin I-set domain
      pfam16650
      Location:711767
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:638710
      Ig; Immunoglobulin domain
    3. NM_001173477.2NP_001166948.1  striated muscle-specific serine/threonine-protein kinase isoform 4

      See identical proteins and their annotated locations for NP_001166948.1

      Status: VALIDATED

      Source sequence(s)
      AC114651
      Consensus CDS
      CCDS48293.1
      UniProtKB/TrEMBL
      A0A0R4J1J0
      Related
      ENSMUSP00000109219.2, ENSMUST00000113589.8
      Conserved Domains (1) summary
      cd20975
      Location:20110
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    4. NM_007463.5NP_031489.4  striated muscle-specific serine/threonine-protein kinase isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114651, AC161346
      Consensus CDS
      CCDS35626.1
      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      UniProtKB/TrEMBL
      E9QQ25
      Related
      ENSMUSP00000084361.6, ENSMUST00000087122.12
      Conserved Domains (8) summary
      cd00096
      Location:62124
      Ig; Immunoglobulin domain
      smart00408
      Location:10821148
      IGc2; Immunoglobulin C-2 Type
      smart00220
      Location:29613213
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam07679
      Location:727816
      I-set; Immunoglobulin I-set domain
      cd14108
      Location:16031859
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:29573213
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:817873
      SPEG_u2; Unstructured region on SPEG complex protein
      cl11960
      Location:744816
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      75351931..75408964
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155020.1XP_036010913.1  striated muscle-specific serine/threonine-protein kinase isoform X11

      Conserved Domains (9) summary
      smart00410
      Location:14141495
      IG_like; Immunoglobulin like
      PHA03247
      Location:320725
      PHA03247; large tegument protein UL36; Provisional
      cd00063
      Location:12971374
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:16131869
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:827883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737826
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:10791082
      Ig; Ig strand A [structural motif]
      cd20975
      Location:884974
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
      cl11960
      Location:10791168
      Ig; Immunoglobulin domain
    2. XM_011238643.3XP_011236945.1  striated muscle-specific serine/threonine-protein kinase isoform X1

      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      Conserved Domains (8) summary
      PHA03247
      Location:19512355
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:22352557
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:26912777
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:16131869
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:29673223
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:827883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737826
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:9881073
      Ig; Immunoglobulin domain
    3. XM_011238644.3XP_011236946.1  striated muscle-specific serine/threonine-protein kinase isoform X2

      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      Conserved Domains (8) summary
      PHA03247
      Location:18922296
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:21762498
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:26322718
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:15541810
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:29083164
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:768824
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:678767
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:9291014
      Ig; Immunoglobulin domain
    4. XM_011238651.3XP_011236953.1  striated muscle-specific serine/threonine-protein kinase isoform X13

      Conserved Domains (3) summary
      PHA03247
      Location:320678
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:827883
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:737826
      I-set; Immunoglobulin I-set domain
    5. XM_030243368.2XP_030099228.1  striated muscle-specific serine/threonine-protein kinase isoform X14

      Conserved Domains (3) summary
      PHA03247
      Location:261619
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:768824
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:678767
      I-set; Immunoglobulin I-set domain
    6. XM_030243273.2XP_030099133.1  striated muscle-specific serine/threonine-protein kinase isoform X8

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:12061610
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14901812
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:19462032
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8681124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:22222478
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755844
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:243328
      Ig; Immunoglobulin domain
    7. XM_017322354.3XP_017177843.1  striated muscle-specific serine/threonine-protein kinase isoform X3

      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      Conserved Domains (8) summary
      PHA03247
      Location:18852289
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:21692491
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:26252711
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:15471803
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:761817
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:671760
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:9221007
      Ig; Immunoglobulin domain
      cl21453
      Location:29013157
      PKc_like; Protein Kinases, catalytic domain
    8. XM_017322375.3XP_017177864.1  striated muscle-specific serine/threonine-protein kinase isoform X6

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:18262230
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:21102432
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:25662652
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:14881744
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:702758
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:612701
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:863948
      Ig; Immunoglobulin domain
      cl21453
      Location:28423098
      PKc_like; Protein Kinases, catalytic domain
    9. XM_011238645.3XP_011236947.1  striated muscle-specific serine/threonine-protein kinase isoform X4

      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      Conserved Domains (8) summary
      PHA03247
      Location:18452249
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:21292451
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:25852671
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:15071763
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:721777
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:631720
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:882967
      Ig; Immunoglobulin domain
      cl21453
      Location:28613117
      PKc_like; Protein Kinases, catalytic domain
    10. XM_011238647.3XP_011236949.1  striated muscle-specific serine/threonine-protein kinase isoform X7

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:17862190
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:20702392
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:25262612
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:14481704
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:662718
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:572661
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:823908
      Ig; Immunoglobulin domain
      cl21453
      Location:28023058
      PKc_like; Protein Kinases, catalytic domain
    11. XM_030243402.2XP_030099262.1  striated muscle-specific serine/threonine-protein kinase isoform X16

      Conserved Domains (3) summary
      PHA03247
      Location:214572
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:721777
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:631720
      I-set; Immunoglobulin I-set domain
    12. XM_030243447.2XP_030099307.1  striated muscle-specific serine/threonine-protein kinase isoform X18

      Conserved Domains (3) summary
      PHA03247
      Location:155513
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:662718
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:572661
      I-set; Immunoglobulin I-set domain
    13. XM_036155145.1XP_036011038.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    14. XM_030243390.2XP_030099250.1  striated muscle-specific serine/threonine-protein kinase isoform X15

      Conserved Domains (3) summary
      PHA03247
      Location:254612
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:761817
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:671760
      I-set; Immunoglobulin I-set domain
    15. XM_017312276.3XP_017167765.1  striated muscle-specific serine/threonine-protein kinase isoform X17

      Conserved Domains (3) summary
      PHA03247
      Location:195553
      PHA03247; large tegument protein UL36; Provisional
      pfam16650
      Location:702758
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:612701
      I-set; Immunoglobulin I-set domain
    16. XM_030243512.2XP_030099372.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    17. XM_011238648.4XP_011236950.1  striated muscle-specific serine/threonine-protein kinase isoform X8

      See identical proteins and their annotated locations for XP_011236950.1

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:12061610
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14901812
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:19462032
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8681124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:22222478
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755844
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:243328
      Ig; Immunoglobulin domain
    18. XM_011238646.3XP_011236948.1  striated muscle-specific serine/threonine-protein kinase isoform X5

      UniProtKB/Swiss-Prot
      Q3TPH8, Q62407, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5
      Conserved Domains (8) summary
      PHA03247
      Location:18352239
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:21192441
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:25752661
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:14971753
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:711767
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:621710
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:872957
      Ig; Immunoglobulin domain
      cl21453
      Location:28513107
      PKc_like; Protein Kinases, catalytic domain
    19. XM_030243494.1XP_030099354.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    20. XM_030243521.1XP_030099381.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    21. XM_006496401.3XP_006496464.1  striated muscle-specific serine/threonine-protein kinase isoform X8

      See identical proteins and their annotated locations for XP_006496464.1

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:12061610
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14901812
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:19462032
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8681124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:22222478
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755844
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:243328
      Ig; Immunoglobulin domain
    22. XM_011238649.4XP_011236951.1  striated muscle-specific serine/threonine-protein kinase isoform X8

      See identical proteins and their annotated locations for XP_011236951.1

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:12061610
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14901812
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:19462032
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8681124
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:22222478
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:755844
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:243328
      Ig; Immunoglobulin domain
    23. XM_030243476.2XP_030099336.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    24. XM_036155175.1XP_036011068.1  striated muscle-specific serine/threonine-protein kinase isoform X19

      Conserved Domains (4) summary
      pfam16650
      Location:82138
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:181
      I-set; Immunoglobulin I-set domain
      cd00096
      Location:917
      Ig; Ig strand B [structural motif]
      cd20975
      Location:139229
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    25. XM_006496403.5XP_006496466.1  striated muscle-specific serine/threonine-protein kinase isoform X10

      See identical proteins and their annotated locations for XP_006496466.1

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (7) summary
      PHA03247
      Location:10871491
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:13711693
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:18271913
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:7491005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21032359
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam07679
      Location:636725
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:124209
      Ig; Immunoglobulin domain
    26. XM_006496404.5XP_006496467.1  striated muscle-specific serine/threonine-protein kinase isoform X10

      See identical proteins and their annotated locations for XP_006496467.1

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (7) summary
      PHA03247
      Location:10871491
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:13711693
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:18271913
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:7491005
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21032359
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam07679
      Location:636725
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:124209
      Ig; Immunoglobulin domain
    27. XM_036155197.1XP_036011090.1  striated muscle-specific serine/threonine-protein kinase isoform X20

      UniProtKB/TrEMBL
      A0A0R4J1J0
      Related
      ENSMUSP00000109217.2, ENSMUST00000113587.8
      Conserved Domains (1) summary
      cd20975
      Location:20110
      IgI_APEG-1_like; Immunoglobulin-like domain of human Aortic Preferentially Expressed Protein-1 (APEG-1) and similar proteins; a member of the I-set of IgSF domains
    28. XM_006496402.3XP_006496465.1  striated muscle-specific serine/threonine-protein kinase isoform X9

      UniProtKB/TrEMBL
      A0A087WSE3
      Conserved Domains (8) summary
      PHA03247
      Location:11461550
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:14301752
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:18861972
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd14108
      Location:8081064
      STKc_SPEG_rpt1; Catalytic kinase domain, first repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      cd14111
      Location:21622418
      STKc_SPEG_rpt2; Catalytic kinase domain, second repeat, of Giant Serine/Threonine Kinase Striated muscle preferentially expressed protein kinase
      pfam16650
      Location:2478
      SPEG_u2; Unstructured region on SPEG complex protein
      pfam07679
      Location:695784
      I-set; Immunoglobulin I-set domain
      cl11960
      Location:183268
      Ig; Immunoglobulin domain
    29. XM_030243348.2XP_030099208.1  striated muscle-specific serine/threonine-protein kinase isoform X12

      Conserved Domains (5) summary
      PHA03247
      Location:237641
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:521843
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00063
      Location:9771063
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam07679
      Location:883973
      I-set; Immunoglobulin I-set domain
      cl21453
      Location:12531509
      PKc_like; Protein Kinases, catalytic domain

    RNA

    1. XR_003947244.2 RNA Sequence