U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Luc7l2 LUC7-like 2 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 192196, updated on 27-Nov-2024

    Summary

    Official Symbol
    Luc7l2provided by MGI
    Official Full Name
    LUC7-like 2 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:2183260
    See related
    Ensembl:ENSMUSG00000029823 AllianceGenome:MGI:2183260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CGI59; Cgi74; 4930471C18Rik
    Summary
    Predicted to enable enzyme binding activity and mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Located in nuclear speck. Orthologous to human LUC7L2 (LUC7 like 2, pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 17.0), bladder adult (RPKM 14.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Luc7l2 in Genome Data Viewer
    Location:
    6 B1; 6 17.85 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (38522996..38586888)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (38551334..38609953)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:38484704-38484891 Neighboring gene nuclear encoded tRNA arginine 1 (anticodon CCT) Neighboring gene formation of mitochondrial complex V assembly factor 1 Neighboring gene STARR-positive B cell enhancer ABC_E2782 Neighboring gene kinesin family member 11 pseudogene Neighboring gene killer cell lectin-like receptor subfamily G, member 2 Neighboring gene Clec2l Hedgehog-responsive enhancer Neighboring gene C-type lectin domain family 2, member L

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splice site recognition IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U1 snRNP IEA
    Inferred from Electronic Annotation
    more info
     
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear speck IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    putative RNA-binding protein Luc7-like 2
    Names
    CGI-74-like SR-rich

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001170848.2NP_001164319.1  putative RNA-binding protein Luc7-like 2 isoform 2

      See identical proteins and their annotated locations for NP_001164319.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC124762, AC161147, AK134191
      UniProtKB/TrEMBL
      Q3UGK2, Q3UZ17
      Conserved Domains (1) summary
      pfam03194
      Location:5241
      LUC7; LUC7 N_terminus
    2. NM_001170849.2NP_001164320.1  putative RNA-binding protein Luc7-like 2 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC124762, AC161147, BC056383
      Consensus CDS
      CCDS51751.1
      UniProtKB/Swiss-Prot
      Q7TNC4
      Related
      ENSMUSP00000124010.2, ENSMUST00000161538.8
      Conserved Domains (2) summary
      COG5200
      Location:5228
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:5241
      LUC7; LUC7 N_terminus
    3. NM_001311099.2NP_001298028.1  putative RNA-binding protein Luc7-like 2 isoform 4

      See identical proteins and their annotated locations for NP_001298028.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains an alternate exon in the 5' region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 4, which has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC124762, AC161147
      Consensus CDS
      CCDS80524.1
      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Related
      ENSMUSP00000125111.2, ENSMUST00000161227.8
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    4. NM_001311100.2NP_001298029.1  putative RNA-binding protein Luc7-like 2 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains an alternate exon in the 5' region, has a distinct 3' terminal exon and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 5, which has a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AC124762, AC161147
      Consensus CDS
      CCDS80525.1
      UniProtKB/TrEMBL
      E9Q715
      Related
      ENSMUSP00000125394.2, ENSMUST00000163047.8
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    5. NM_001331222.1NP_001318151.1  putative RNA-binding protein Luc7-like 2 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) contains three alternate exons in the 5' region and initiates translation at an alternate start codon, and lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (6) has a distinct N-terminus and is shorter than isoform 1.
      Source sequence(s)
      AC124762, AC161147, AK046307, AK147889, CJ255376
      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    6. NM_001331223.1NP_001318152.1  putative RNA-binding protein Luc7-like 2 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 5' exons and initiates translation at a downstream start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (7) is shorter than isoform 1.
      Source sequence(s)
      AC124762, AC161147, AK140271, AK147889, AK153527, CJ255376
      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    7. NM_138680.3NP_619621.2  putative RNA-binding protein Luc7-like 2 isoform 1

      See identical proteins and their annotated locations for NP_619621.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC124762, AC161147
      Consensus CDS
      CCDS20015.1
      UniProtKB/Swiss-Prot
      Q7TNC4, Q99LM5, Q99PC3
      UniProtKB/TrEMBL
      Q3UGK2
      Related
      ENSMUSP00000055254.5, ENSMUST00000057692.11
      Conserved Domains (1) summary
      pfam03194
      Location:5241
      LUC7; LUC7 N_terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      38522996..38586888
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165939.1XP_036021832.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    2. XM_036165936.1XP_036021829.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    3. XM_036165942.1XP_036021835.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    4. XM_036165941.1XP_036021834.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    5. XM_036165946.1XP_036021839.1  putative RNA-binding protein Luc7-like 2 isoform X11

      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    6. XM_036165931.1XP_036021824.1  putative RNA-binding protein Luc7-like 2 isoform X6

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    7. XM_036165934.1XP_036021827.1  putative RNA-binding protein Luc7-like 2 isoform X8

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    8. XM_036165933.1XP_036021826.1  putative RNA-binding protein Luc7-like 2 isoform X7

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:14238
      LUC7; LUC7 N_terminus
    9. XM_036165938.1XP_036021831.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    10. XM_036165932.1XP_036021825.1  putative RNA-binding protein Luc7-like 2 isoform X6

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    11. XM_036165935.1XP_036021828.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    12. XM_030255229.2XP_030111089.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    13. XM_030255226.2XP_030111086.1  putative RNA-binding protein Luc7-like 2 isoform X6

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    14. XM_036165940.1XP_036021833.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    15. XM_036165930.1XP_036021823.1  putative RNA-binding protein Luc7-like 2 isoform X3

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:61275
      LUC7; LUC7 N_terminus
    16. XM_006505747.5XP_006505810.1  putative RNA-binding protein Luc7-like 2 isoform X4

      See identical proteins and their annotated locations for XP_006505810.1

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:41245
      LUC7; LUC7 N_terminus
    17. XM_006505748.5XP_006505811.1  putative RNA-binding protein Luc7-like 2 isoform X5

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:41245
      LUC7; LUC7 N_terminus
    18. XM_030255233.2XP_030111093.1  putative RNA-binding protein Luc7-like 2 isoform X11

      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    19. XM_036165928.1XP_036021821.1  putative RNA-binding protein Luc7-like 2 isoform X1

      Conserved Domains (1) summary
      pfam03194
      Location:5312
      LUC7; LUC7 N_terminus
    20. XM_036165929.1XP_036021822.1  putative RNA-binding protein Luc7-like 2 isoform X2

      Conserved Domains (1) summary
      pfam03194
      Location:5312
      LUC7; LUC7 N_terminus
    21. XM_036165945.1XP_036021838.1  putative RNA-binding protein Luc7-like 2 isoform X11

      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    22. XM_006505750.4XP_006505813.1  putative RNA-binding protein Luc7-like 2 isoform X6

      See identical proteins and their annotated locations for XP_006505813.1

      UniProtKB/TrEMBL
      Q3UGK2
      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    23. XM_030255232.2XP_030111092.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    24. XM_030255235.2XP_030111095.1  putative RNA-binding protein Luc7-like 2 isoform X11

      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    25. XM_036165943.1XP_036021836.1  putative RNA-binding protein Luc7-like 2 isoform X10

      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    26. XM_036165948.1XP_036021841.1  putative RNA-binding protein Luc7-like 2 isoform X13

      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    27. XM_030255236.2XP_030111096.1  putative RNA-binding protein Luc7-like 2 isoform X12

      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    28. XM_036165949.1XP_036021842.1  putative RNA-binding protein Luc7-like 2 isoform X13

      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    29. XM_030255237.2XP_030111097.1  putative RNA-binding protein Luc7-like 2 isoform X12

      Conserved Domains (1) summary
      pfam03194
      Location:26240
      LUC7; LUC7 N_terminus
    30. XM_036165950.1XP_036021843.1  putative RNA-binding protein Luc7-like 2 isoform X14

      UniProtKB/TrEMBL
      E9Q715
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    31. XM_036165951.1XP_036021844.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    32. XM_036165937.1XP_036021830.1  putative RNA-binding protein Luc7-like 2 isoform X9

      UniProtKB/TrEMBL
      Q05CX5, Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus
    33. XM_036165944.1XP_036021837.1  putative RNA-binding protein Luc7-like 2 isoform X11

      UniProtKB/TrEMBL
      Q3U5L2
      Conserved Domains (1) summary
      pfam03194
      Location:1188
      LUC7; LUC7 N_terminus