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    Zfp24 zinc finger protein 24 [ Mus musculus (house mouse) ]

    Gene ID: 59057, updated on 9-Dec-2024

    Summary

    Official Symbol
    Zfp24provided by MGI
    Official Full Name
    zinc finger protein 24provided by MGI
    Primary source
    MGI:MGI:1929704
    See related
    Ensembl:ENSMUSG00000051469 AllianceGenome:MGI:1929704
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    KOX17; ZF-12; Znf24; Zfp191; 3526401F17Rik; 5033419P20Rik
    Summary
    Enables sequence-specific DNA binding activity. Involved in myelination. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb primordium; and sensory organ. Orthologous to human ZNF24 (zinc finger protein 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 5.8), CNS E14 (RPKM 4.0) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp24 in Genome Data Viewer
    Location:
    18 A2; 18 12.55 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (24142774..24155294, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (24009717..24020813, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene zinc finger and SCAN domain containing 30 Neighboring gene zinc finger protein 397 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:24145637-24145876 Neighboring gene STARR-seq mESC enhancer starr_44051 Neighboring gene zinc finger protein 35 Neighboring gene STARR-positive B cell enhancer ABC_E8705 Neighboring gene STARR-seq mESC enhancer starr_44054 Neighboring gene ribosomal protein S8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_44055 Neighboring gene predicted gene, 18085

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein 24
    Names
    hypomyelinated CNS protein
    zfp-191
    zinc finger protein 191
    zinc finger protein ZF-12

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357447.1NP_001344376.1  zinc finger protein 24

      Status: VALIDATED

      Source sequence(s)
      AC126807, BP764437
      Consensus CDS
      CCDS29098.1
      UniProtKB/Swiss-Prot
      Q5MDG8, Q91VN1, Q9WUQ0
      Conserved Domains (3) summary
      smart00431
      Location:48159
      SCAN; leucine rich region
      COG5048
      Location:305358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253273
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001357448.1NP_001344377.1  zinc finger protein 24

      Status: VALIDATED

      Source sequence(s)
      AC126807, BP764437
      Consensus CDS
      CCDS29098.1
      UniProtKB/Swiss-Prot
      Q5MDG8, Q91VN1, Q9WUQ0
      Related
      ENSMUSP00000122579.2, ENSMUST00000153337.2
      Conserved Domains (3) summary
      smart00431
      Location:48159
      SCAN; leucine rich region
      COG5048
      Location:305358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253273
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_021559.3NP_067534.2  zinc finger protein 24

      See identical proteins and their annotated locations for NP_067534.2

      Status: VALIDATED

      Source sequence(s)
      AC126807, BC054832, BP764437, CD562306
      Consensus CDS
      CCDS29098.1
      UniProtKB/Swiss-Prot
      Q5MDG8, Q91VN1, Q9WUQ0
      Related
      ENSMUSP00000064637.6, ENSMUST00000066497.12
      Conserved Domains (3) summary
      smart00431
      Location:48159
      SCAN; leucine rich region
      COG5048
      Location:305358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253273
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      24142774..24155294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161225.1XP_036017118.1  zinc finger protein 24 isoform X1

      UniProtKB/Swiss-Prot
      Q5MDG8, Q91VN1, Q9WUQ0
      Conserved Domains (3) summary
      smart00431
      Location:48159
      SCAN; leucine rich region
      COG5048
      Location:305358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253273
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. XM_036161226.1XP_036017119.1  zinc finger protein 24 isoform X1

      UniProtKB/Swiss-Prot
      Q5MDG8, Q91VN1, Q9WUQ0
      Conserved Domains (3) summary
      smart00431
      Location:48159
      SCAN; leucine rich region
      COG5048
      Location:305358
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:253273
      ZF_C2H2; C2H2 Zn finger [structural motif]