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    Brd10 bromodomain containing 10 [ Mus musculus (house mouse) ]

    Gene ID: 240613, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Brd10provided by MGI
    Official Full Name
    bromodomain containing 10provided by MGI
    Primary source
    MGI:MGI:2444398
    See related
    Ensembl:ENSMUSG00000046138 AllianceGenome:MGI:2444398
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm9832; mKIAA2026; 9930021J03Rik
    Summary
    Is expressed in olfactory epithelium and vomeronasal organ. Orthologous to human BRD10 (bromodomain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 5.1), whole brain E14.5 (RPKM 5.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Brd10 in Genome Data Viewer
    Location:
    19 C1; 19 24.3 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (29691802..29784273, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (29714402..29806548, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36126 Neighboring gene STARR-seq mESC enhancer starr_45893 Neighboring gene STARR-seq mESC enhancer starr_45894 Neighboring gene melan-A Neighboring gene STARR-positive B cell enhancer ABC_E7643 Neighboring gene RAN binding protein 6 Neighboring gene STARR-seq mESC enhancer starr_45896 Neighboring gene STARR-seq mESC enhancer starr_45897 Neighboring gene predicted gene, 41832 Neighboring gene predicted gene, 36209

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA2026

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein KIAA2026 homolog
    Names
    bromo domain

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172836.4 → NP_766424.2  uncharacterized protein KIAA2026 homolog

      Status: VALIDATED

      Source sequence(s)
      AC120159
      UniProtKB/TrEMBL
      H3BL88
      Related
      ENSMUSP00000135696.2, ENSMUST00000175726.8
      Conserved Domains (3) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      pfam05672
      Location:253 → 292
      MAP7; MAP7 (E-MAP-115) family
      cl20817
      Location:245 → 289
      GBP_C; Guanylate-binding protein, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      29691802..29784273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527072.5 → XP_006527135.1  uncharacterized protein KIAA2026 homolog isoform X4

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (5) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      PRK03918
      Location:601 → 799
      PRK03918; DNA double-strand break repair ATPase Rad50
      TIGR03502
      Location:1251 → 1377
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1472 → 1828
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:937 → 1074
      PARM

    2. XM_017318195.3 → XP_017173684.1  uncharacterized protein KIAA2026 homolog isoform X6

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (4) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      TIGR03502
      Location:1190 → 1316
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1411 → 1767
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:876 → 1013
      PARM

    3. XM_017318193.3 → XP_017173682.1  uncharacterized protein KIAA2026 homolog isoform X2

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (4) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      TIGR03502
      Location:1323 → 1449
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1544 → 1900
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:1009 → 1146
      PARM

    4. XM_017318194.3 → XP_017173683.1  uncharacterized protein KIAA2026 homolog isoform X5

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (3) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      TIGR03502
      Location:1220 → 1346
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1441 → 1797
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    5. XM_006527069.5 → XP_006527132.1  uncharacterized protein KIAA2026 homolog isoform X1

      UniProtKB/TrEMBL
      H3BKP8, H3BL88
      Related
      ENSMUSP00000135473.2, ENSMUST00000177155.8
      Conserved Domains (5) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      PRK03918
      Location:703 → 901
      PRK03918; DNA double-strand break repair ATPase Rad50
      TIGR03502
      Location:1353 → 1479
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1574 → 1930
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:1039 → 1176
      PARM

    6. XM_006527070.5 → XP_006527133.1  uncharacterized protein KIAA2026 homolog isoform X3

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (5) summary
      cd04369
      Location:137 → 193
      Bromodomain; Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
      PRK03918
      Location:668 → 866
      PRK03918; DNA double-strand break repair ATPase Rad50
      TIGR03502
      Location:1318 → 1444
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1539 → 1895
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:1004 → 1141
      PARM

    7. XM_017318196.3 → XP_017173685.1  uncharacterized protein KIAA2026 homolog isoform X8

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (4) summary
      PRK03918
      Location:421 → 619
      PRK03918; DNA double-strand break repair ATPase Rad50
      TIGR03502
      Location:1071 → 1197
      lipase_Pla1_cef; extracellular lipase, Pla-1/cef family
      pfam05109
      Location:1292 → 1648
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      pfam17061
      Location:757 → 894
      PARM

    8. XM_036161593.1 → XP_036017486.1  uncharacterized protein KIAA2026 homolog isoform X7

      UniProtKB/TrEMBL
      H3BL88
      Conserved Domains (2) summary
      PRK03918
      Location:473 → 671
      PRK03918; DNA double-strand break repair ATPase Rad50
      pfam05109
      Location:1344 → 1700
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

    9. XM_030250937.2 → XP_030106797.1  uncharacterized protein KIAA2026 homolog isoform X9

      UniProtKB/TrEMBL
      H3BJL2
      Conserved Domains (1) summary
      PRK13042
      Location:876 → 981
      PRK13042; superantigen-like protein SSL4; Reviewed

    10. XM_030250938.1 → XP_030106798.1  uncharacterized protein KIAA2026 homolog isoform X10

      UniProtKB/TrEMBL
      H3BJL2
      Related
      ENSMUSP00000135031.3, ENSMUST00000175764.9
      Conserved Domains (1) summary
      PRK13042
      Location:871 → 976
      PRK13042; superantigen-like protein SSL4; Reviewed

    RNA

    1. XR_003952789.2 RNA Sequence

    2. XR_001782588.3 RNA Sequence

    3. XR_003952791.2 RNA Sequence

    4. XR_004940143.1 RNA Sequence

    5. XR_001782590.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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