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    Thap2 THAP domain containing, apoptosis associated protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 66816, updated on 27-Nov-2024

    Summary

    Official Symbol
    Thap2provided by MGI
    Official Full Name
    THAP domain containing, apoptosis associated protein 2provided by MGI
    Primary source
    MGI:MGI:1914066
    See related
    Ensembl:ENSMUSG00000020137 AllianceGenome:MGI:1914066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900040O07Rik; 9030625G08Rik
    Summary
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleolus. Predicted to be active in nucleus. Orthologous to human THAP2 (THAP domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 5.3), CNS E11.5 (RPKM 4.9) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Thap2 in Genome Data Viewer
    Location:
    10 D2; 10 63.51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (115204303..115220340, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (115368398..115384435, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53632 Neighboring gene STARR-seq mESC enhancer starr_27937 Neighboring gene STARR-seq mESC enhancer starr_27939 Neighboring gene STARR-seq mESC enhancer starr_27942 Neighboring gene transmembrane protein 19 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E1128 Neighboring gene predicted gene, 53633 Neighboring gene zinc finger, C3H1-type containing Neighboring gene STARR-positive B cell enhancer mm9_chr10:114916114-114916415 Neighboring gene leucine rich repeat containing G protein coupled receptor 5 Neighboring gene STARR-seq mESC enhancer starr_27944 Neighboring gene RIKEN cDNA A930009A15 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    THAP domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025780.4NP_080056.1  THAP domain-containing protein 2

      See identical proteins and their annotated locations for NP_080056.1

      Status: VALIDATED

      Source sequence(s)
      AK051198, AK081303, BG073155, BU698918, CX208940
      Consensus CDS
      CCDS24179.1
      UniProtKB/Swiss-Prot
      Q9D305
      Related
      ENSMUSP00000151353.2, ENSMUST00000218842.2
      Conserved Domains (1) summary
      pfam05485
      Location:482
      THAP; THAP domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      115204303..115220340 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)