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    C18h5orf63 similar to human chromosome 5 open reading frame 63 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100174910, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C18h5orf63provided by RGD
    Official Full Name
    similar to human chromosome 5 open reading frame 63provided by RGD
    Primary source
    RGD:2299854
    See related
    EnsemblRapid:ENSRNOG00000013738 AllianceGenome:RGD:2299854
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in mitochondrion. Orthologous to human C5orf63 (chromosome 5 open reading frame 63). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 89.3), Kidney (RPKM 86.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See C18h5orf63 in Genome Data Viewer
    Location:
    18q12.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (52622143..52640110, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (50424079..50442172, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (52031825..52049756, complement)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene lamin B1 Neighboring gene membrane associated ring-CH-type finger 3 Neighboring gene small ribosomal subunit protein uS3-like Neighboring gene uncharacterized LOC120098149 Neighboring gene mitochondrial ribosomal protein L30, pseudogene 9 Neighboring gene nucleophosmin pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Morgenstern M, et al. Cell Metab, 2021 Dec 7. PMID 34800366, Free PMC Article
    2. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC188899, MGC188903

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glutaredoxin-like protein C5orf63 homolog
    Names
    glutaredoxin-like protein YDR286C homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001131003.2 → NP_001124475.1  glutaredoxin-like protein C5orf63 homolog isoform 1

      See identical proteins and their annotated locations for NP_001124475.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A6IX72, G3V7R5
      Related
      ENSRNOP00000107270.1, ENSRNOT00000133123.1
      Conserved Domains (1) summary
      pfam05768
      Location:32 → 105
      DUF836; Glutaredoxin-like domain (DUF836)

    2. NM_001419689.1 → NP_001406618.1  glutaredoxin-like protein C5orf63 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      B2RYV3

    3. NM_001419690.1 → NP_001406619.1  glutaredoxin-like protein C5orf63 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A6IX72, G3V7R5
      Related
      ENSRNOP00000110988.1, ENSRNOT00000146127.1

    4. NM_001419691.1 → NP_001406620.1  glutaredoxin-like protein C5orf63 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000018
      UniProtKB/TrEMBL
      A6IX72, G3V7R5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      52622143..52640110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063277040.1 → XP_063133110.1  glutaredoxin-like protein C5orf63 homolog isoform X5

    2. XM_039096518.2 → XP_038952446.2  glutaredoxin-like protein C5orf63 homolog isoform X4

    3. XM_063277036.1 → XP_063133106.1  glutaredoxin-like protein C5orf63 homolog isoform X2

    4. XM_006254736.5 → XP_006254798.2  glutaredoxin-like protein C5orf63 homolog isoform X1

      UniProtKB/TrEMBL
      A6IX72, G3V7R5
      Conserved Domains (1) summary
      pfam05768
      Location:32 → 105
      DUF836; Glutaredoxin-like domain (DUF836)

    5. XM_063277038.1 → XP_063133108.1  glutaredoxin-like protein C5orf63 homolog isoform X3

      UniProtKB/TrEMBL
      B2RYV3

    6. XM_063277034.1 → XP_063133104.1  glutaredoxin-like protein C5orf63 homolog isoform X1

      UniProtKB/TrEMBL
      A6IX72, G3V7R5

    7. XM_063277037.1 → XP_063133107.1  glutaredoxin-like protein C5orf63 homolog isoform X3

      UniProtKB/TrEMBL
      B2RYV3
      Related
      ENSRNOP00000018368.5, ENSRNOT00000018368.9

    8. XM_063277035.1 → XP_063133105.1  glutaredoxin-like protein C5orf63 homolog isoform X2

    9. XM_063277039.1 → XP_063133109.1  glutaredoxin-like protein C5orf63 homolog isoform X5

    Nucleotide Protein Strain
    Heading Accession and Version

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