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    Sprr2d small proline-rich protein 2D [ Rattus norvegicus (Norway rat) ]

    Gene ID: 102550699, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sprr2dprovided by RGD
    Official Full Name
    small proline-rich protein 2Dprovided by RGD
    Primary source
    RGD:7559659
    See related
    EnsemblRapid:ENSRNOG00000009168 AllianceGenome:RGD:7559659
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in female gonad development. Predicted to act upstream of or within response to estradiol. Predicted to be located in cytoplasm and nucleus. Orthologous to several human genes including SPRR2D (small proline rich protein 2D). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Uterus (RPKM 19.0) and Thymus (RPKM 4.0) See more
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    Genomic context

    See Sprr2d in Genome Data Viewer
    Location:
    2q34
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (180565685..180566282, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (177870082..177870679, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (192480676..192481990, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene small proline-rich protein 2E-like Neighboring gene small proline rich protein 2B Neighboring gene small proline-rich protein 2 like 1 Neighboring gene small proline-rich protein 2D-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in female gonad development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to estradiol ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cornified envelope IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small proline-rich protein 2D
    Names
    small proline-rich protein 2I-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001408914.1NP_001395843.1  small proline-rich protein 2D

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      D3ZAR3
      Related
      ENSRNOP00000012135.5, ENSRNOT00000012135.7

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      180565685..180566282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)