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    Slc36a3 solute carrier family 36, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303148, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Slc36a3provided by RGD
    Official Full Name
    solute carrier family 36, member 3provided by RGD
    Primary source
    RGD:1309092
    See related
    EnsemblRapid:ENSRNOG00000021310 AllianceGenome:RGD:1309092
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable amino acid transmembrane transporter activity. Predicted to be involved in carboxylic acid transport and proton transmembrane transport. Predicted to be active in vacuolar membrane. Orthologous to human SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 60.8) See more
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    Genomic context

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    See Slc36a3 in Genome Data Viewer
    Location:
    10q22
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (39744226..39774120, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (39243531..39273433, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (40462752..40490259, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 69 Neighboring gene ganglioside GM2 activator Neighboring gene uncharacterized LOC134480794 Neighboring gene solute carrier family 36 member 2 Neighboring gene uncharacterized LOC134480795 Neighboring gene solute carrier family 36 member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables L-alanine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables L-proline transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-alanine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in glycine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proline transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proton transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    proton-coupled amino acid transporter 3
    Names
    proton/amino acid transporter 3
    solute carrier family 36 (proton/amino acid symporter), member 3
    tramdorin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024764.1 → NP_001019935.1  proton-coupled amino acid transporter 3

      See identical proteins and their annotated locations for NP_001019935.1

      Status: PROVISIONAL

      Source sequence(s)
      BC097463
      UniProtKB/Swiss-Prot
      Q4V8B1
      UniProtKB/TrEMBL
      A6HEL0
      Related
      ENSRNOP00000037827.4, ENSRNOT00000037274.7
      Conserved Domains (1) summary
      cl00456
      Location:52 → 458
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      39744226..39774120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008767685.4 → XP_008765907.1  proton-coupled amino acid transporter 3 isoform X1

      See identical proteins and their annotated locations for XP_008765907.1

      UniProtKB/Swiss-Prot
      Q4V8B1
      UniProtKB/TrEMBL
      A6HEL0
      Conserved Domains (1) summary
      cl00456
      Location:52 → 458
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. XM_006246381.4 → XP_006246443.1  proton-coupled amino acid transporter 3 isoform X2

      Conserved Domains (1) summary
      cl00456
      Location:52 → 385
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. XM_039085937.2 → XP_038941865.1  proton-coupled amino acid transporter 3 isoform X3

      UniProtKB/TrEMBL
      A6HEL0
      Conserved Domains (1) summary
      cl00456
      Location:39 → 361
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. XM_039085939.2 → XP_038941867.1  proton-coupled amino acid transporter 3 isoform X3

      UniProtKB/TrEMBL
      A6HEL0
      Conserved Domains (1) summary
      cl00456
      Location:39 → 361
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    5. XM_039085938.2 → XP_038941866.1  proton-coupled amino acid transporter 3 isoform X3

      UniProtKB/TrEMBL
      A6HEL0
      Conserved Domains (1) summary
      cl00456
      Location:39 → 361
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V8B1.1 GenPept UniProtKB/Swiss-Prot:Q4V8B1

    Gene LinkOut

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