Shisa4 shisa family member 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Shisa4provided by RGD
Official Full Name: shisa family member 4provided by RGD
Primary source: RGD:1312041
See related: EnsemblRapid:ENSRNOG00000007369 AllianceGenome:RGD:1312041
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Prmp; Tmem58; RGD1312041
Summary: Predicted to be located in membrane. Orthologous to human SHISA4 (shisa family member 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 389.1), Brain (RPKM 294.6) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 13q13

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	13	NC_086031.1 (49351518..49355599, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	13	NC_051348.1 (46799735..46803816, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	13	NC_005112.4 (52193989..52197205, complement)

Chromosome 13 - NC_086031.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

At the O4+ oligodendrocyte differentiation stage, a new proline-rich transmembrane protein, Prmp, is expressed. At the plasma membrane, Prmp displays adhesive properties that may link the extracellular matrix to the actin cytoskeleton.
Title: Identification of a novel oligodendrocyte cell adhesion protein using gene expression profiling.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein shisa-4

Names: proline rich membrane protein; shisa homolog 4; transmembrane protein 58

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.