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    spe-48 UBA domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 245997, updated on 9-Dec-2024

    Summary

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    Official Symbol
    spe-48
    Official Full Name
    UBA domain-containing protein
    Primary source
    WormBase:WBGene00021771
    Locus tag
    CELE_Y51F10.10
    See related
    AllianceGenome:WB:WBGene00021771
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ubiquitin binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be part of ESCRT I complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See spe-48 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (1950594..1958527, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Aa_trans domain-containing protein;Amino acid transporter transmembrane domain-containing protein Neighboring gene EGF-like domain-containing protein Neighboring gene Defect at low temperature protein 1 Neighboring gene EGF-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental genetics of chromosome I spermatogenesis-defective mutants in the nematode Caenorhabditis elegans. L'Hernault SW, et al. Genetics, 1988 Oct. PMID 3197956, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of ESCRT I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ESCRT I complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UBA domain-containing protein
    NP_001293398.1
    • Confirmed by transcript evidence
    NP_001293399.1
    • Confirmed by transcript evidence
    NP_001293400.1
    • Confirmed by transcript evidence
    NP_001293401.1
    • Confirmed by transcript evidence
    NP_740794.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      1950594..1958527 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001306469.2 → NP_001293398.1  UBA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293398.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5MBH3
      Conserved Domains (1) summary
      cl21463
      Location:280 → 309
      UBA_like_SF; UBA domain-like superfamily

    2. NM_170811.6 → NP_740794.1  UBA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_740794.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8WTK0
      Conserved Domains (1) summary
      cl21463
      Location:305 → 334
      UBA_like_SF; UBA domain-like superfamily

    3. NM_001306470.3 → NP_001293399.1  UBA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293399.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5M5Q2
      Conserved Domains (1) summary
      cl21463
      Location:265 → 294
      UBA_like_SF; UBA domain-like superfamily

    4. NM_001306471.3 → NP_001293400.1  UBA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293400.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5MD76
      Conserved Domains (1) summary
      cl21463
      Location:290 → 319
      UBA_like_SF; UBA domain-like superfamily

    5. NM_001306472.3 → NP_001293401.1  UBA domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293401.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5MK34
      Conserved Domains (1) summary
      cl21463
      Location:43 → 72
      UBA_like_SF; UBA domain-like superfamily
    Nucleotide Protein
    Heading Accession and Version

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