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    R11H6.5 DZF domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    R11H6.5
    Official Full Name
    DZF domain-containing protein
    Primary source
    WormBase:WBGene00011253
    Locus tag
    CELE_R11H6.5
    See related
    AllianceGenome:WB:WBGene00011253
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity and double-stranded RNA binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to be located in nucleus. Is expressed in pharyngeal neurons. Orthologous to human ILF2 (interleukin enhancer binding factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See R11H6.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (14610713..14612222, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene PEST proteolytic signal-containing nuclear protein;Shugoshin_C domain-containing protein;Uncharacterized protein Neighboring gene Cyclin-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables double-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DZF domain-containing protein
    NP_506614.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14610713..14612222 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074213.6 → NP_506614.2  DZF domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506614.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62349
      Conserved Domains (1) summary
      pfam07528
      Location:113 → 354
      DZF; DZF domain
    Nucleotide Protein
    Heading Accession and Version

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