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    Y119D3B.14 Tr-type G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191043, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y119D3B.14
    Official Full Name
    Tr-type G domain-containing protein
    Primary source
    WormBase:WBGene00022491
    Locus tag
    CELE_Y119D3B.14
    See related
    AllianceGenome:WB:WBGene00022491
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in mitochondrial translation and ribosome disassembly. Is expressed in intestine. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 39. Orthologous to human GFM2 (GTP dependent ribosome recycling factor mitochondrial 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y119D3B.14 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (1185248..1193812, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Cadherin domain-containing protein Neighboring gene ncRNA Neighboring gene Enhancer of AKt-1 null Neighboring gene DUF19 domain-containing protein Neighboring gene putative 26S proteasome complex subunit dss-1 Neighboring gene Large ribosomal subunit protein mL45

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosome disassembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tr-type G domain-containing protein
    NP_497345.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1185248..1193812 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064944.7 → NP_497345.2  Tr-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497345.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      D4AFK0, Q95Y73
      Conserved Domains (1) summary
      COG0480
      Location:23 → 727
      FusA; Translation elongation factor EF-G, a GTPase [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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