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    Y73B6BL.29 tRNA pseudouridine synthase [ Caenorhabditis elegans ]

    Gene ID: 260252, updated on 4-Jan-2025

    Summary

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    Official Symbol
    Y73B6BL.29
    Official Full Name
    tRNA pseudouridine synthase
    Primary source
    WormBase:WBGene00022250
    Locus tag
    CELE_Y73B6BL.29
    See related
    AllianceGenome:WB:WBGene00022250
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable pseudouridine synthase activity. Predicted to be involved in tRNA pseudouridine synthesis. Orthologous to human PUSL1 (pseudouridine synthase like 1). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See Y73B6BL.29 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (6321929..6323567)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Putative inactive caspase subunit p14 Neighboring gene Thioredoxin domain-containing protein Neighboring gene RRM domain-containing protein Neighboring gene U6 snRNA-associated Sm-like protein LSm8

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables pseudouridine synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables pseudouridine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables tRNA pseudouridine(38-40) synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tRNA pseudouridine synthase
    NP_001380157.1
    • Confirmed by transcript evidence
    NP_500962.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      6321929..6323567
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068561.7 → NP_500962.1  tRNA pseudouridine synthase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500962.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XD5
      Conserved Domains (2) summary
      COG0101
      Location:5 → 315
      TruA; tRNA U38,U39,U40 pseudouridine synthase TruA [Translation, ribosomal structure and biogenesis]
      cl00130
      Location:62 → 303
      PseudoU_synth; Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi)

    2. NM_001392314.1 → NP_001380157.1  tRNA pseudouridine synthase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      V6CKE5
      Conserved Domains (1) summary
      PRK00021
      Location:24 → 164
      truA; tRNA pseudouridine(38-40) synthase TruA
    Nucleotide Protein
    Heading Accession and Version

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