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    W02B12.11 Beta-1,4-N-acetylgalactosaminyltransferase [ Caenorhabditis elegans ]

    Gene ID: 174754, updated on 9-Dec-2024

    Summary

    Official Symbol
    W02B12.11
    Official Full Name
    Beta-1,4-N-acetylgalactosaminyltransferase
    Primary source
    WormBase:WBGene00012206
    Locus tag
    CELE_W02B12.11
    See related
    AllianceGenome:WB:WBGene00012206
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity and beta-1,4-N-acetylgalactosaminyltransferase activity. Predicted to be involved in glycosphingolipid biosynthetic process and protein glycosylation. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including body wall musculature; hermaphrodite gonad; hypodermis; intestine; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See W02B12.11 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (11473861..11476025)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Mitoferrin Neighboring gene tRNA (guanine-N(7)-)-methyltransferase Neighboring gene Uncharacterized protein Neighboring gene non-specific serine/threonine protein kinase Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables beta-1,4-N-acetylgalactosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glycosphingolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Beta-1,4-N-acetylgalactosaminyltransferase
    NP_496449.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11473861..11476025
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064048.7NP_496449.1  Beta-1,4-N-acetylgalactosaminyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496449.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EGS9
      Conserved Domains (1) summary
      cd00899
      Location:158375
      b4GalT; Beta-4-Galactosyltransferase is involved in the formation of the poly-N-acetyllactosamine core structures present in glycoproteins and glycosphingolipids