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    metl-9 DREV methyltransferase [ Caenorhabditis elegans ]

    Gene ID: 188034, updated on 2-Nov-2024

    Summary

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    Official Symbol
    metl-9
    Official Full Name
    DREV methyltransferase
    Primary source
    WormBase:WBGene00020199
    Locus tag
    CELE_T03G11.6
    See related
    AllianceGenome:WB:WBGene00020199
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein-L-histidine N-pros-methyltransferase activity. Predicted to be involved in methylation. Orthologous to human METTL9 (methyltransferase 9, His-X-His N1(pi)-histidine). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See metl-9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (5177519..5179150, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Zinc finger C2HC domain-containing protein T03G11.3 Neighboring gene Serpentine Receptor, class T Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 6mA-Sniper: Quantifying 6mA sites in eukaryotes at single-nucleotide resolution. Zhang J, et al. Sci Adv, 2023 Oct 20. PMID 37862411, Free PMC Article
    2. 6mA-METL-9 axis regulates innate immunity in C. elegans. Wu T, et al. Cell Res, 2023 Aug. PMID 37337028, Free PMC Article
    3. A novel N(6)-Deoxyadenine methyltransferase METL-9 modulates C. elegans immunity via dichotomous mechanisms. Ma C, et al. Cell Res, 2023 Aug. PMID 37271765, Free PMC Article
    4. N6-adenosine methylation of ribosomal RNA affects lipid oxidation and stress resistance. Liberman N, et al. Sci Adv, 2020 Apr. PMID 32494643, Free PMC Article
    5. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-L-histidine N-pros-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DREV methyltransferase
    NP_508880.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5177519..5179150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076479.8 → NP_508880.2  DREV methyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508880.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22123
      Conserved Domains (1) summary
      pfam05219
      Location:16 → 281
      DREV; DREV methyltransferase
    Nucleotide Protein
    Heading Accession and Version

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