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    Il24 interleukin 24 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 170819, updated on 27-Nov-2024

    Summary

    Official Symbol
    Il24provided by RGD
    Official Full Name
    interleukin 24provided by RGD
    Primary source
    RGD:621484
    See related
    EnsemblRapid:ENSRNOG00000004470 AllianceGenome:RGD:621484
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    If2e; Mda7; Mda-7
    Summary
    Predicted to enable cytokine activity. Involved in several processes, including cellular response to interleukin-4; cellular response to lipopolysaccharide; and serine phosphorylation of STAT protein. Located in extracellular space. Biomarker of periodontal disease. Orthologous to human IL24 (interleukin 24). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Spleen (RPKM 33.6), Thymus (RPKM 5.9) and 4 other tissues See more
    Orthologs
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    Genomic context

    See Il24 in Genome Data Viewer
    Location:
    13q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (44905362..44910760, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (42353089..42358487, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (47618451..47623849, complement)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene polymeric immunoglobulin receptor Neighboring gene Fc mu receptor Neighboring gene interleukin 20 Neighboring gene small ribosomal subunit protein eS10-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    General protein information

    Preferred Names
    interleukin-24
    Names
    IL-24
    cytokine-like protein Mob-5
    interferon 2e

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133311.1NP_579845.1  interleukin-24 precursor

      See identical proteins and their annotated locations for NP_579845.1

      Status: PROVISIONAL

      Source sequence(s)
      AF269251
      UniProtKB/Swiss-Prot
      Q9JI24
      UniProtKB/TrEMBL
      A0A7R8C3K9, A6IC08
      Related
      ENSRNOP00000006106.2, ENSRNOT00000006106.5
      Conserved Domains (1) summary
      cl02501
      Location:50177
      IL10; Interleukin 10

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      44905362..44910760 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)