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    Bltp3b bridge-like lipid transfer protein family member 3B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 363009, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bltp3bprovided by RGD
    Official Full Name
    bridge-like lipid transfer protein family member 3Bprovided by RGD
    Primary source
    RGD:1594520
    See related
    EnsemblRapid:ENSRNOG00000050317 AllianceGenome:RGD:1594520
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Uhrf1bp1l
    Summary
    Predicted to enable GARP complex binding activity; lipid transfer activity; and protein homodimerization activity. Predicted to be involved in early endosome to Golgi transport and intermembrane lipid transfer. Predicted to be located in cytosol and early endosome. Orthologous to human BLTP3B (bridge-like lipid transfer protein family member 3B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 588.9), Kidney (RPKM 156.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Bltp3b in Genome Data Viewer
    Location:
    7q13
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (26068948..26149033)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (24181635..24261720)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (30408519..30455783)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479655 Neighboring gene actin related protein 6 Neighboring gene ankyrin repeat and sterile alpha motif domain containing 1B Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC134479858

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A novel syntaxin 6-interacting protein, SHIP164, regulates syntaxin 6-dependent sorting from early endosomes. Otto GP, et al. Traffic, 2010 May. PMID 20163565
    2. JUNB-FBXO21-ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy. Lin Z, et al. Aging Cell, 2021 Feb. PMID 33450132, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GARP complex binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables lipid transfer activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in early endosome to Golgi transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in intermembrane lipid transfer ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    bridge-like lipid transfer protein family member 3B
    Names
    UHRF1 (ICBP90) binding protein 1-like
    UHRF1 binding protein 1-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108753.1 → NP_001102223.1  bridge-like lipid transfer protein family member 3B

      See identical proteins and their annotated locations for NP_001102223.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473960
      UniProtKB/TrEMBL
      A0A8I5Y0N1, A6IFS5, M0R8V0
      Conserved Domains (1) summary
      pfam12624
      Location:3 → 89
      Chorein_N; N-terminal region of Chorein or VPS13

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      26068948..26149033
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039079668.2 → XP_038935596.1  bridge-like lipid transfer protein family member 3B isoform X3

      UniProtKB/TrEMBL
      A0A8I5Y0N1, A0A8I5ZSC2
      Related
      ENSRNOP00000081344.1, ENSRNOT00000118426.2
      Conserved Domains (1) summary
      pfam12624
      Location:5 → 96
      Chorein_N; N-terminal region of Chorein or VPS13

    2. XM_063264009.1 → XP_063120079.1  bridge-like lipid transfer protein family member 3B isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y0N1
      Related
      ENSRNOP00000065905.4, ENSRNOT00000072733.4

    3. XM_039079667.2 → XP_038935595.1  bridge-like lipid transfer protein family member 3B isoform X2

      UniProtKB/TrEMBL
      A0A8I5Y0N1, A6IFS6
      Related
      ENSRNOP00000077042.1, ENSRNOT00000096260.2
    Nucleotide Protein Strain
    Heading Accession and Version

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