Dnaaf10 dynein axonemal assembly factor 10 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Dnaaf10provided by MGI
Official Full Name: dynein axonemal assembly factor 10provided by MGI
Primary source: MGI:MGI:2144224
See related: Ensembl:ENSMUSG00000078970 AllianceGenome:MGI:2144224
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: HZGJ; Wdr92
Summary: Predicted to enable ubiquitin binding activity. Predicted to be involved in axonemal dynein complex assembly. Predicted to be located in dynein axonemal particle. Predicted to be part of RPAP3/R2TP/prefoldin-like complex. Orthologous to human DNAAF10 (dynein axonemal assembly factor 10). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 3.6), placenta adult (RPKM 3.4) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 A2; 11 9.75 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (17161893..17185200)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (17211893..17235200)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

BB100320 (e-PCR)
- UniSTS:208640

AI553587 (e-PCR)
- UniSTS:180159

NoName (e-PCR)
- UniSTS:493255

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables ubiquitin binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in apoptotic process	IEA Inferred from Electronic Annotation more info
involved_in axonemal dynein complex assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of RPAP3/R2TP/prefoldin-like complex	IEA Inferred from Electronic Annotation more info
part_of RPAP3/R2TP/prefoldin-like complex	ISO Inferred from Sequence Orthology more info
located_in dynein axonemal particle	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: dynein axonemal assembly factor 10

Names: WD repeat domain 92; WD repeat-containing protein 92; WD repeat-containing protein Monad

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_178909.4 → NP_849240.1 dynein axonemal assembly factor 10

See identical proteins and their annotated locations for NP_849240.1

Status: VALIDATED

Source sequence(s)

AK033294, AL713926, BY794211

Consensus CDS

CCDS24450.1

UniProtKB/Swiss-Prot

Q8BGF3

Related

ENSMUSP00000040938.7, ENSMUST00000046955.7

Conserved Domains (3) summary

COG2319
Location:2 → 348

WD40; WD40 repeat [General function prediction only]

sd00039
Location:21 → 64

7WD40; WD40 repeat [structural motif]

cl02567
Location:21 → 348

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...