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    Nat9 N-acetyltransferase 9 (GCN5-related, putative) [ Mus musculus (house mouse) ]

    Gene ID: 66176, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Nat9provided by MGI
    Official Full Name
    N-acetyltransferase 9 (GCN5-related, putative)provided by MGI
    Primary source
    MGI:MGI:1913426
    See related
    Ensembl:ENSMUSG00000015542 AllianceGenome:MGI:1913426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110028N05Rik
    Summary
    Predicted to enable tubulin N-terminal N-acetyltransferase activity. Predicted to be part of protein-containing complex. Is expressed in embryo. Orthologous to human NAT9 (N-acetyltransferase 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 30.3), ovary adult (RPKM 10.1) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Nat9 in Genome Data Viewer
    Location:
    11 E2; 11 80.68 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115073655..115078682, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115182829..115187856, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RAB37, member RAS oncogene family Neighboring gene CD300 molecule like family member F Neighboring gene STARR-positive B cell enhancer ABC_E11499 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115019296-115019604 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115024157-115024344 Neighboring gene STARR-positive B cell enhancer ABC_E91 Neighboring gene NHERF family PDZ scaffold protein 1 Neighboring gene STARR-positive B cell enhancer mm9_chr11:115048516-115048817 Neighboring gene transmembrane protein 104 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115088135-115088322 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115088428-115088537 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115092913-115093101 Neighboring gene glutamate receptor, ionotropic, NMDA2C (epsilon 3) Neighboring gene STARR-positive B cell enhancer ABC_E44 Neighboring gene ferredoxin reductase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility. Gu J, et al. Cell Death Differ, 2023 Jul. PMID 37142655, Free PMC Article
    2. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables tubulin N-terminal N-acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of protein-containing complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    alpha/beta-tubulin-N-acetyltransferase 9
    Names
    novel acetyltransferase protein
    NP_001349818.1
    NP_001349819.1
    NP_001349820.1
    NP_001349821.1
    NP_079676.1
    XP_036012784.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362889.1 → NP_001349818.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL606487
      Consensus CDS
      CCDS25622.1
      UniProtKB/Swiss-Prot
      Q3UG98, Q8C1G5, Q9D151
      Related
      ENSMUSP00000099330.2, ENSMUST00000103041.8
      Conserved Domains (1) summary
      pfam13302
      Location:14 → 161
      Acetyltransf_3; Acetyltransferase (GNAT) domain

    2. NM_001362890.1 → NP_001349819.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL606487
      Consensus CDS
      CCDS25622.1
      UniProtKB/Swiss-Prot
      Q3UG98, Q8C1G5, Q9D151
      Related
      ENSMUSP00000099327.2, ENSMUST00000103038.8
      Conserved Domains (1) summary
      pfam13302
      Location:14 → 161
      Acetyltransf_3; Acetyltransferase (GNAT) domain

    3. NM_001362891.1 → NP_001349820.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL606487
      Conserved Domains (1) summary
      pfam13302
      Location:52 → 131
      Acetyltransf_3; Acetyltransferase (GNAT) domain

    4. NM_001362892.1 → NP_001349821.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL606487, CX208013
      Conserved Domains (1) summary
      pfam13302
      Location:24 → 102
      Acetyltransf_3; Acetyltransferase (GNAT) domain

    5. NM_025400.4 → NP_079676.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform 1

      See identical proteins and their annotated locations for NP_079676.1

      Status: VALIDATED

      Source sequence(s)
      AL606487
      Consensus CDS
      CCDS25622.1
      UniProtKB/Swiss-Prot
      Q3UG98, Q8C1G5, Q9D151
      Related
      ENSMUSP00000099329.5, ENSMUST00000103040.11
      Conserved Domains (1) summary
      pfam13302
      Location:14 → 161
      Acetyltransf_3; Acetyltransferase (GNAT) domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      115073655..115078682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156891.1 → XP_036012784.1  alpha/beta-tubulin-N-acetyltransferase 9 isoform X1

      Conserved Domains (1) summary
      pfam13302
      Location:24 → 102
      Acetyltransf_3; Acetyltransferase (GNAT) domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UG98.2 GenPept UniProtKB/Swiss-Prot:Q3UG98

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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