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    PSP 3-phosphoserine phosphatase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838445, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PSP
    Official Full Name
    3-phosphoserine phosphatase
    Primary source
    TAIR:AT1G18640
    Locus tag
    AT1G18640
    See related
    Araport:AT1G18640
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-phosphoserine phosphatase; 3-PHOSPHOSERINE PHOSPHATASE; phosphoserine phosphatase 1; PSP1
    Summary
    Encodes a 3-phosphoserine phosphatase acting in the last step of serine biosynthesis within the chloroplast. Essential for embryo, pollen and root development.
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    Genomic context

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    See PSP in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (6416169..6418693, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene LONGIFOLIA protein Neighboring gene glycine-rich RNA-binding protein 6 Neighboring gene plasmodesmata callose-binding protein 3 Neighboring gene zinc finger (C3HC4-type RING finger) family protein Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overexpression of PSP1 enhances growth of transgenic Arabidopsis plants under ambient air conditions. Han X, et al. Plant Mol Biol, 2017 Jul. PMID 28455648
    2. The phosphorylated pathway of serine biosynthesis is essential both for male gametophyte and embryo development and for root growth in Arabidopsis. Cascales-Miñana B, et al. Plant Cell, 2013 Jun. PMID 23771893, Free PMC Article
    3. Plastidic pathway of serine biosynthesis. Molecular cloning and expression of 3-phosphoserine phosphatase from Arabidopsis thaliana. Ho CL, et al. J Biol Chem, 1999 Apr 16. PMID 10196182
    4. Deficiency in the Phosphorylated Pathway of Serine Biosynthesis Perturbs Sulfur Assimilation. Anoman AD, et al. Plant Physiol, 2019 May. PMID 30787133, Free PMC Article
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results suggest a close correlation between the function of PPSB and photorespiration, and also nitrogen metabolism in leaves.
      Title: Overexpression of PSP1 enhances growth of transgenic Arabidopsis plants under ambient air conditions.
    2. Data indicate that lack of phosphoserine phosphatase PSP1 (At1g18640) activity delayed embryo development, leading to aborted embryos that could be classified as early curled cotyledons.
      Title: The phosphorylated pathway of serine biosynthesis is essential both for male gametophyte and embryo development and for root growth in Arabidopsis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001332354.1
    NM_202129.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables L-phosphoserine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables L-phosphoserine phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables magnesium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within L-serine biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in L-serine metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within embryo development ending in seed dormancy IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within root development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within sulfur amino acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastid IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    3-phosphoserine phosphatase
    NP_973858.1
    • 3-phosphoserine phosphatase (PSP); FUNCTIONS IN: phosphoserine phosphatase activity; INVOLVED IN: L-serine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), Phosphoserine phosphatase SerB (InterPro:IPR004469), HAD-superfamily hydrolase, subfamily IB, PSPase-like (InterPro:IPR006383); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      6416169..6418693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_202129.3 → NP_973858.1  3-phosphoserine phosphatase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82796, Q9FZ85
      UniProtKB/TrEMBL
      A0A178W417, A0A5S9V0Q6, A0A654ECY8
      Conserved Domains (1) summary
      PLN02954
      Location:72 → 295
      PLN02954; phosphoserine phosphatase

    2. NM_001332354.1 → NP_001320464.1  3-phosphoserine phosphatase [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMY1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82796.2

    Gene LinkOut

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