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    Ms4a6b membrane-spanning 4-domains, subfamily A, member 6B [ Mus musculus (house mouse) ]

    Gene ID: 69774, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ms4a6bprovided by MGI
    Official Full Name
    membrane-spanning 4-domains, subfamily A, member 6Bprovided by MGI
    Primary source
    MGI:MGI:1917024
    See related
    Ensembl:ENSMUSG00000024677 AllianceGenome:MGI:1917024
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810027D10Rik
    Summary
    Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane and trans-Golgi network. Is expressed in genitourinary system. Orthologous to several human genes including MS4A6A (membrane spanning 4-domains A6A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in spleen adult (RPKM 14.6), thymus adult (RPKM 14.5) and 16 other tissues See more
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    Genomic context

    See Ms4a6b in Genome Data Viewer
    Location:
    19 A; 19 8.44 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (11495923..11507767)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (11518559..11530403)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene membrane-spanning 4-domains, subfamily A, member 6C Neighboring gene expressed sequence BE692007 Neighboring gene STARR-positive B cell enhancer ABC_E7634 Neighboring gene STARR-positive B cell enhancer ABC_E4266 Neighboring gene STARR-positive B cell enhancer ABC_E11672 Neighboring gene STARR-positive B cell enhancer ABC_E8739 Neighboring gene predicted gene 8369 Neighboring gene membrane-spanning 4-domains, subfamily A, member 4D Neighboring gene membrane-spanning 4-domains subfamily A member 6D-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    membrane-spanning 4-domains subfamily A member 6B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027209.3NP_081485.2  membrane-spanning 4-domains subfamily A member 6B

      See identical proteins and their annotated locations for NP_081485.2

      Status: PROVISIONAL

      Source sequence(s)
      AC165168
      Consensus CDS
      CCDS29601.1
      UniProtKB/Swiss-Prot
      Q8BK83, Q99N09, Q9D8W9
      Related
      ENSMUSP00000025580.4, ENSMUST00000025580.10
      Conserved Domains (1) summary
      pfam04103
      Location:47204
      CD20; CD20-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      11495923..11507767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)