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    FLO10 Flo10p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853977, updated on 9-Dec-2024

    Summary

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    Official Symbol
    FLO10
    Official Full Name
    Flo10p
    Primary source
    SGD:S000001810
    Locus tag
    YKR102W
    See related
    AllianceGenome:SGD:S000001810; FungiDB:YKR102W; VEuPathDB:YKR102W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable D-mannose binding activity. Involved in flocculation and invasive growth in response to glucose limitation. Located in cell periphery. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See FLO10 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (646356..649865)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Skg1p Neighboring gene Sir1p Neighboring gene putative multidrug transporter NFT1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification and functional study of a new FLO10-derivative gene from the industrial flocculating yeast SPSC01. He LY, et al. J Ind Microbiol Biotechnol, 2012 Aug. PMID 22466447
    2. Review: the dominant flocculation genes of Saccharomyces cerevisiae constitute a new subtelomeric gene family. Teunissen AW, et al. Yeast, 1995 Sep 15. PMID 7502576
    3. Functional divergence of gene duplicates through ectopic recombination. Christiaens JF, et al. EMBO Rep, 2012 Dec. PMID 23070367, Free PMC Article
    4. Construction of flocculent Kluyveromyces marxianus strains suitable for high-temperature ethanol fermentation. Nonklang S, et al. Biosci Biotechnol Biochem, 2009 May. PMID 19420680
    5. A Saccharomyces gene family involved in invasive growth, cell-cell adhesion, and mating. Guo B, et al. Proc Natl Acad Sci U S A, 2000 Oct 24. PMID 11027318, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-mannose binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in filamentous growth of a population of unicellular organisms IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in flocculation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in invasive growth in response to glucose limitation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Flo10p
    NP_013028.1
    • Member of the FLO family of cell wall flocculation proteins; not expressed in most lab strains; overproduction induces flocculation that can be inhibited by mannose, sucrose, or glucose; overproduction also promotes haploid invasive growth and diploid filamentous growth

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      646356..649865
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179892.1 → NP_013028.1  TPA: Flo10p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013028.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VXG3, P36170
      UniProtKB/TrEMBL
      A7A062
      Conserved Domains (2) summary
      pfam07691
      Location:135 → 271
      PA14; PA14 domain
      pfam13928
      Location:996 → 1037
      Flocculin_t3; Flocculin type 3 repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P36170.1

    Gene LinkOut

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