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    NBA1 Nba1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854084, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NBA1
    Official Full Name
    Nba1p
    Primary source
    SGD:S000005431
    Locus tag
    YOL070C
    See related
    AllianceGenome:SGD:S000005431; FungiDB:YOL070C; VEuPathDB:YOL070C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in axial cellular bud site selection; establishment of protein localization; and regulation of protein localization to cell division site. Located in cellular bud neck septin collar; cellular bud neck split septin rings; and cellular bud scar. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See NBA1 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (197220..198725, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Thp1p Neighboring gene succinate dehydrogenase assembly factor SDH5 Neighboring gene kinetochore-associated Ndc80 complex subunit NUF2 Neighboring gene histone deacetylase HST1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The septin-associated kinase Gin4 recruits Gps1 to the site of cell division. Meitinger F, et al. Mol Biol Cell, 2017 Apr 1. PMID 28148650, Free PMC Article
    2. Fine-tuning the orientation of the polarity axis by Rga1, a Cdc42 GTPase-activating protein. Miller KE, et al. Mol Biol Cell, 2017 Dec 15. PMID 29074565, Free PMC Article
    3. Septin-associated proteins Aim44 and Nis1 traffic between the bud neck and the nucleus in the yeast Saccharomyces cerevisiae. Perez AM, et al. Cytoskeleton (Hoboken), 2019 Jan. PMID 30341817, Free PMC Article
    4. A memory system of negative polarity cues prevents replicative aging. Meitinger F, et al. Cell, 2014 Nov 20. PMID 25416945
    5. Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast. Estrem C, et al. Mol Biol Cell, 2019 Jul 22. PMID 31067146, Free PMC Article

    See all (53) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in axial cellular bud site selection IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in establishment of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of protein localization to cell division site IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud neck HDA PubMed 
    located_in cellular bud neck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud neck IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cellular bud neck septin collar IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud neck split septin rings IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud scar IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cellular bud scar IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nba1p
    NP_014571.1
    • Protein involved in axial bud site selection; prevents repolarization of cells at previous division sites; recruited by Aim44p and Nap1p to the cell cortex and to cytokinesis remnants (bud scars) where it prevents Rsr1p-mediated activation of Cdc24p, the Cdc42p GEF; localizes to the cytoplasm, and the cell division site prior to being stably recruited to cytokinesis remnants; establishes the transient localization of Rga1p, a Cdc42p GAP, at bud scars along with Nis1p; potential Cdc28p substrate

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      197220..198725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183325.1 → NP_014571.1  TPA: Nba1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014571.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1Z7, Q08229
      UniProtKB/TrEMBL
      A6ZNE0, C7GK37, C8ZHP5, N1NZ52
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08229.1

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