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    YML6 mitochondrial 54S ribosomal protein YmL6 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854983, updated on 9-Dec-2024

    Summary

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    Official Symbol
    YML6
    Official Full Name
    mitochondrial 54S ribosomal protein YmL6
    Primary source
    SGD:S000004487
    Locus tag
    YML025C
    See related
    AllianceGenome:SGD:S000004487; FungiDB:YML025C; VEuPathDB:YML025C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uL4m
    Summary
    A structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Part of mitochondrial large ribosomal subunit. Orthologous to human MRPL4 (mitochondrial ribosomal protein L4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See YML6 in Genome Data Viewer
    Location:
    chromosome: XIII
    Exon count:
    2
    Sequence:
    Chromosome: XIII; NC_001145.3 (224406..225365, complement)

    Chromosome XIII - NC_001145.3Genomic Context describing neighboring genes Neighboring gene Yox1p Neighboring gene ribosomal 40S subunit protein S18B Neighboring gene ribosomal 40S subunit protein S17A Neighboring gene Smc5-Smc6 complex subunit NSE5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001145.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mitochondrial ribosomal proteins (MRPs) of yeast. Graack HR, et al. Biochem J, 1998 Feb 1. PMID 9445368, Free PMC Article
    2. Spp382p interacts with multiple yeast splicing factors, including possible regulators of Prp43 DExD/H-Box protein function. Pandit S, et al. Genetics, 2009 Sep. PMID 19581443, Free PMC Article
    3. Identification of proteins associated with the yeast mitochondrial RNA polymerase by tandem affinity purification. Markov DA, et al. Yeast, 2009 Aug. PMID 19536766, Free PMC Article
    4. Identification and characterization of the genes for mitochondrial ribosomal proteins of Saccharomyces cerevisiae. Kitakawa M, et al. Eur J Biochem, 1997 Apr 15. PMID 9151978
    5. Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, et al. Science, 2014 Mar 28. PMID 24675956, Free PMC Article

    See all (49) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of mitochondrial large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 54S ribosomal protein YmL6
    NP_013687.1
    • Mitochondrial ribosomal protein of the large subunit; has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001145.3 Reference assembly

      Range
      224406..225365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182383.1 → NP_013687.1  TPA: mitochondrial 54S ribosomal protein YmL6 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013687.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZE9, P51998
      UniProtKB/TrEMBL
      A6ZM37, B3LLM7, C8ZEH9, G2WK27, N1P0Y4
      Conserved Domains (1) summary
      pfam00573
      Location:58 → 272
      Ribosomal_L4; Ribosomal protein L4/L1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P51998.1

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