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    HDA3 histone deacetylase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823605, updated on 18-Sep-2024

    Summary

    Official Symbol
    HDA3
    Official Full Name
    histone deacetylase 3
    Primary source
    TAIR:AT3G44750
    Locus tag
    AT3G44750
    See related
    Araport:AT3G44750
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATHD2A; HD2A; HDT1; HISTONE DEACETYLASE 2A; histone deacetylase 3
    Summary
    Encodes a histone deacetylase. Controls the development of adaxial/abaxial leaf polarity. Two lines with RNAi-directed against this gene show reduced Agrobacterium-mediated DNA transformation of the roots.
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    Genomic context

    See HDA3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Sequence:
    Chromosome: 3; NC_003074.8 (16297656..16299876)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene kinesin-like protein 1 Neighboring gene PHYTOSULFOKINE 3 PRECURSOR Neighboring gene Class II aaRS and biotin synthetases superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene miscRNA

    Bibliography

    Interactions

    General gene information

    NM_001203083.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables histone deacetylase activity PubMed 
    enables histone deacetylase activity PubMed 
    enables protein binding PubMed 
    Component Evidence Code Pubs
    located_in nucleolus PubMed 
    located_in nucleolus PubMed 
    located_in nucleus  

    General protein information

    Preferred Names
    histone deacetylase 3
    NP_001190012.1
    • histone deacetylase 3 (HDA3); CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-type (InterPro:IPR007087), Nucleoplasmin (InterPro:IPR004301); BEST Arabidopsis thaliana protein match is: histone deacetylase 2B (TAIR:AT5G22650.1).
    NP_566872.1
    • histone deacetylase 3 (HDA3); FUNCTIONS IN: histone deacetylase activity, zinc ion binding, nucleic acid binding; INVOLVED IN: DNA mediated transformation, polarity specification of adaxial/abaxial axis; LOCATED IN: nucleolus; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087); BEST Arabidopsis thaliana protein match is: histone deacetylase 2B (TAIR:AT5G22650.1); Has 5980 Blast hits to 4690 proteins in 449 species: Archae - 12; Bacteria - 394; Metazoa - 2639; Fungi - 927; Plants - 442; Viruses - 82; Other Eukaryotes - 1484 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      16297656..16299876
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114344.4 → NP_566872.1  histone deacetylase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566872.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22238, Q9FVE6
      UniProtKB/TrEMBL
      A0A5S9XIC3, A0A7G2ERJ5
      Conserved Domains (2) summary
      pfam13912
      Location:220 → 242
      zf-C2H2_6; C2H2-type zinc finger
      pfam17800
      Location:3 → 92
      NPL; Nucleoplasmin-like domain
    2. NM_001203083.1 → NP_001190012.1  histone deacetylase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190012.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ERJ5, F4J378
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