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    CG11454 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33175, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11454provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031224
    Locus tag
    Dmel_CG11454
    See related
    AllianceGenome:FB:FBgn0031224
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg11454; Dmel\CG11454; dRbm7
    Summary
    Predicted to enable mRNA binding activity and single-stranded RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to be active in nucleus. Orthologous to several human genes including RBM7 (RNA binding motif protein 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11454 in Genome Data Viewer
    Location:
    21B3-21B3; 2-0.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (143323..144227)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (143323..144227)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 15 kDa subunit Neighboring gene uncharacterized protein Neighboring gene oven mitt Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Pseudouridine synthase 10

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Molleston JM, et al. Genes Dev, 2016 Jul 15. PMID 27474443, Free PMC Article
    2. The drosophila melanogaster genome: translation factors and RNA binding proteins. Lasko P. J Cell Biol, 2000 Jul 24. PMID 10908586, Free PMC Article
    3. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
    4. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
    5. Next-generation large-scale binary protein interaction network for Drosophila melanogaster. Tang HW, et al. Nat Commun, 2023 Apr 15. PMID 37061542, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables single-stranded RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of alternative mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11454-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      143323..144227
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134653.4 → NP_608497.1  uncharacterized protein Dmel_CG11454 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608497.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BIE3, Q9VPK4
      Related
      FBpp0077775
      Conserved Domains (2) summary
      COG0724
      Location:70 → 210
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12336
      Location:69 → 143
      RRM_RBM7_like; RNA recognition motif in RNA-binding protein 7 (RBM7) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BIE3 Q5BIE3
    Q95RA2 Q95RA2
    Q9VPK4 Q9VPK4

    Gene LinkOut

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