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    CG3108 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31506, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG3108provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029807
    Locus tag
    Dmel_CG3108
    See related
    AllianceGenome:FB:FBgn0029807
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG3108
    Summary
    Predicted to enable metallocarboxypeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in embryonic dorsal epidermis; embryonic head epidermis; and embryonic ventral epidermis. Human ortholog(s) of this gene implicated in familial febrile seizures 11 and familial temporal lobe epilepsy 5. Orthologous to human CPA6 (carboxypeptidase A6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG3108 in Genome Data Viewer
    Location:
    5C2-5C2; 1-14 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5777195..5781620, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5671228..5675653, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44832 Neighboring gene uncharacterized protein Neighboring gene mir-4963 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effect of heritable symbionts on maternally-derived embryo transcripts. Mateos M, et al. Sci Rep, 2019 Jun 20. PMID 31222094, Free PMC Article
    2. Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo. Deignan L, et al. PLoS Genet, 2016 Jul. PMID 27379389, Free PMC Article
    3. X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. Legube G, et al. Genes Dev, 2006 Apr 1. PMID 16547175, Free PMC Article
    4. Protein interaction mapping: a Drosophila case study. Formstecher E, et al. Genome Res, 2005 Mar. PMID 15710747, Free PMC Article
    5. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables metallocarboxypeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metallocarboxypeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG3108-PA
    NP_572262.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5777195..5781620 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132034.2 → NP_572262.1  uncharacterized protein Dmel_CG3108 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572262.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W475
      Related
      FBpp0070798
      Conserved Domains (2) summary
      cd03860
      Location:821 → 1112
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      pfam02244
      Location:730 → 797
      Propep_M14; Carboxypeptidase activation peptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W475 Q9W475

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