Rab19 Rab19 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Rab19provided by FlyBase
Official Full Name: Rab19provided by FlyBase
Primary source: FLYBASE:FBgn0015793
Locus tag: Dmel_CG7062
See related: AllianceGenome:FB:FBgn0015793
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: AAF50452; CG7062; Dmel\CG7062; DmRab19; DRABR3; DRabRP3; O18339; Rab-r3; Rab-RP3; rab19; Rab19/RP3; Rab19s
Summary: Predicted to enable GTPase activity. Involved in enteroendocrine cell differentiation and regulation of cell differentiation involved in tissue homeostasis. Located in Golgi apparatus; neuronal cell body; and synapse. Is expressed in several structures, including Bolwig organ; adult head; brain; imaginal disc; and synaptic neuropil domain. Orthologous to several human genes including RAB43 (RAB43, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (8297018..8298506)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (8290118..8291606)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables GTPase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in Rab protein signal transduction	ISS Inferred from Sequence or Structural Similarity more info
involved_in autophagosome assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in enteroendocrine cell differentiation	IGI Inferred from Genetic Interaction more info	PubMed
involved_in enteroendocrine cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of cell differentiation involved in tissue homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in vesicle-mediated transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in neuronal cell body	IDA Inferred from Direct Assay more info	PubMed
located_in recycling endosome	HDA more info	PubMed
located_in synapse	HDA more info	PubMed
located_in synapse	IDA Inferred from Direct Assay more info	PubMed
located_in vesicle	ISS Inferred from Sequence or Structural Similarity more info