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    CG11664 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31033, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11664provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040341
    Locus tag
    Dmel_CG11664
    See related
    AllianceGenome:FB:FBgn0040341
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG11664; EG:BACR7A4.3; SP193
    Summary
    Predicted to enable serine-type endopeptidase activity. Involved in sexual reproduction. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11664 in Genome Data Viewer
    Location:
    1D2-1D2; 1-0 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (875732..876612)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (769765..770645)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Leucine zipper like transcription regulator 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Predicted seminal astacin-like protease is required for processing of reproductive proteins in Drosophila melanogaster. Ravi Ram K, et al. Proc Natl Acad Sci U S A, 2006 Dec 5. PMID 17116868, Free PMC Article
    2. Exposure to endosulfan influences sperm competition in Drosophila melanogaster. Misra S, et al. Sci Rep, 2014 Dec 11. PMID 25503806, Free PMC Article
    3. Evidence for positive selection on Drosophila melanogaster seminal fluid protease homologs. Wong A, et al. Mol Biol Evol, 2008 Mar. PMID 18056920
    4. An ectopic expression screen reveals the protective and toxic effects of Drosophila seminal fluid proteins. Mueller JL, et al. Genetics, 2007 Feb. PMID 17110486, Free PMC Article
    5. Sustained post-mating response in Drosophila melanogaster requires multiple seminal fluid proteins. Ram KR, et al. PLoS Genet, 2007 Dec. PMID 18085830, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sexual reproduction HEP PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11664-PA
    NP_569865.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      875732..876612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130509.2 → NP_569865.1  uncharacterized protein Dmel_CG11664 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569865.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F7VJR9, Q9V3J7
      Related
      FBpp0070158
      Conserved Domains (2) summary
      smart00020
      Location:38 → 237
      Tryp_SPc; Trypsin-like serine protease
      cl21584
      Location:38 → 239
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V3J7 Q9V3J7

    Gene LinkOut

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