U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    mRpL22 mitochondrial ribosomal protein L22 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32662, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    mRpL22provided by FlyBase
    Official Full Name
    mitochondrial ribosomal protein L22provided by FlyBase
    Primary source
    FLYBASE:FBgn0030786
    Locus tag
    Dmel_CG4742
    See related
    AllianceGenome:FB:FBgn0030786
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4742; Dmel\CG4742; L22
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Is expressed in several structures, including adult head; anterior endoderm; dorsal pharyngeal muscle cell; embryonic/larval midgut primordium; and mesoderm. Orthologous to human MRPL22 (mitochondrial ribosomal protein L22). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See mRpL22 in Genome Data Viewer
    Location:
    15A7-15A8; 1-55 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16783933..16785092)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16677966..16679125)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene gone early Neighboring gene uncharacterized protein Neighboring gene Tweedlealpha Neighboring gene inflated Neighboring gene uncharacterized protein Neighboring gene SIN3-associated polypeptide 30 Neighboring gene Rrp45

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Genome-Wide Analysis of Drosophila RBf2 Protein Highlights the Diversity of RB Family Targets and Possible Role in Regulation of Ribosome Biosynthesis. Wei Y, et al. G3 (Bethesda), 2015 May 20. PMID 25999584, Free PMC Article
    2. Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription. Ni JQ, et al. Genes Dev, 2006 Jul 15. PMID 16816001, Free PMC Article
    3. Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. Suzuki T, et al. J Biol Chem, 2001 Jun 15. PMID 11279069
    4. Mitochondrial DNA quality control in the female germline requires a unique programmed mitophagy. Palozzi JM, et al. Cell Metab, 2022 Nov 1. PMID 36323236
    5. The SIN3 deacetylase complex represses genes encoding mitochondrial proteins: implications for the regulation of energy metabolism. Pile LA, et al. J Biol Chem, 2003 Sep 26. PMID 12865422

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables structural constituent of ribosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial large ribosomal subunit ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of mitochondrial large ribosomal subunit TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    mitochondrial ribosomal protein L22
    Names
    CG4742-PA
    mRpL22-PA
    ribosomal protein L22

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16783933..16785092
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078655.4 → NP_523379.2  mitochondrial ribosomal protein L22 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523379.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SZC3, Q9VXB5
      Related
      FBpp0074104
      Conserved Domains (1) summary
      pfam00237
      Location:95 → 197
      Ribosomal_L22; Ribosomal protein L22p/L17e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VXB5.2 Q9VXB5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous