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    Bacc Bacchus [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33462, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Baccprovided by FlyBase
    Official Full Name
    Bacchusprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031453
    Locus tag
    Dmel_CG9894
    See related
    AllianceGenome:FB:FBgn0031453
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Liang-2.54; bacc; CG9894; clone 2.54; Dmel\CG9894
    Summary
    Involved in behavioral response to ethanol. Located in nucleoplasm. Is expressed in several structures, including adult brain cell body rind; adult head; ganglia; gland; and nephrocyte. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Bacc in Genome Data Viewer
    Location:
    23A3-23A3; 2-7 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2752445..2757975)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2752445..2757975)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Hepatocyte growth factor regulated tyrosine kinase substrate Neighboring gene uncharacterized protein Neighboring gene Cwc25 Neighboring gene Phosphoglycerate kinase Neighboring gene long non-coding RNA:CR44772 Neighboring gene SNAP associated protein Neighboring gene HemK methyltransferase 2 Neighboring gene Transportin-Serine/Arginine rich Neighboring gene Sorting nexin 21

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The effect of Drosophila attP40 background on the glomerular organization of Or47b olfactory receptor neurons. Duan Q, et al. G3 (Bethesda), 2023 Apr 11. PMID 36695023, Free PMC Article
    2. Biases in Drosophila melanogaster protein trap screens. Aleksic J, et al. BMC Genomics, 2009 May 28. PMID 19476619, Free PMC Article
    3. Mutations in Bacchus reveal a tyramine-dependent nuclear regulator for acute ethanol sensitivity in Drosophila. Chen J, et al. Neuropharmacology, 2013 Apr. PMID 23142736
    4. Moesin is a major regulator of centrosome behavior in epithelial cells with extra centrosomes. Sabino D, et al. Curr Biol, 2015 Mar 30. PMID 25772448, Free PMC Article
    5. Comprehensive Characterization of the Complex lola Locus Reveals a Novel Role in the Octopaminergic Pathway via Tyramine Beta-Hydroxylase Regulation. Dinges N, et al. Cell Rep, 2017 Dec 5. PMID 29212035

    See all (70) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Loss-of-function mutations in the CG9894 gene (now named Bacchus or Bacc) attenuate ethanol sensitivity in flies.
      Title: Mutations in Bacchus reveal a tyramine-dependent nuclear regulator for acute ethanol sensitivity in Drosophila.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in behavioral response to ethanol IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    bacchus
    Names
    Bacc-PA
    Bacc-PB
    Bacc-PC
    Bacc-PD
    CG9894-PA
    CG9894-PB
    CG9894-PC
    CG9894-PD
    baccus

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2752445..2757975
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273031.2 → NP_001259960.1  bacchus, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259960.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VQF7

    2. NM_001258921.3 → NP_001245850.1  bacchus, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245850.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VQF7

    3. NM_134862.4 → NP_608706.1  bacchus, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608706.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VQF7
      Related
      FBpp0077397

    4. NM_164498.3 → NP_722833.1  bacchus, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722833.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VQF7
      Related
      FBpp0077398
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VQF7.1 Q9VQF7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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