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    CG17219 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33515, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG17219provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031494
    Locus tag
    Dmel_CG17219
    See related
    AllianceGenome:FB:FBgn0031494
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG17219; METTL18
    Summary
    Predicted to enable protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in regulation of translation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in organism. Orthologous to human METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG17219 in Genome Data Viewer
    Location:
    23C4-23C5; 2-8 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3029253..3030616)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3029253..3030616)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene alpha1,4-galactosyltransferase 1 Neighboring gene pre-mRNA processing factor 40 Neighboring gene Splicing factor 3b subunit 2 Neighboring gene antisense RNA:CR44147 Neighboring gene beta4GalNAcTB pilot Neighboring gene uncharacterized protein Neighboring gene Seryl-tRNA synthetase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The 18S ribosomal RNA m(6) A methyltransferase Mettl5 is required for normal walking behavior in Drosophila. Leismann J, et al. EMBO Rep, 2020 Jul 3. PMID 32350990, Free PMC Article
    2. During Drosophila disc regeneration, JAK/STAT coordinates cell proliferation with Dilp8-mediated developmental delay. Katsuyama T, et al. Proc Natl Acad Sci U S A, 2015 May 5. PMID 25902518, Free PMC Article
    3. Automated identification of putative methyltransferases from genomic open reading frames. Katz JE, et al. Mol Cell Proteomics, 2003 Aug. PMID 12872006
    4. Analysis of Ras-induced overproliferation in Drosophila hemocytes. Asha H, et al. Genetics, 2003 Jan. PMID 12586708, Free PMC Article
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables S-adenosylmethionine-dependent methyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables protein-L-histidine N-tele-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG17219-PA
    NP_608740.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3029253..3030616
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_134896.5 → NP_608740.2  uncharacterized protein Dmel_CG17219 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608740.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VQK8
      Related
      FBpp0077335
      Conserved Domains (1) summary
      pfam12847
      Location:141 → 261
      Methyltransf_18; Methyltransferase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYR9 Q8SYR9
    Q9VQK8 Q9VQK8

    Gene LinkOut

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