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    Alp12 Alkaline phosphatase 12 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35218, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Alp12provided by FlyBase
    Official Full Name
    Alkaline phosphatase 12provided by FlyBase
    Primary source
    FLYBASE:FBgn0032779
    Locus tag
    Dmel_CG16771
    See related
    AllianceGenome:FB:FBgn0032779
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG16771; Dmel\CG16771
    Summary
    Predicted to enable alkaline phosphatase activity. Predicted to be located in cell surface. Is expressed in adult head and adult heart. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Alp12 in Genome Data Viewer
    Location:
    37D7-37E1; 2-54 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19424050..19429224)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19424050..19429224)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Paxillin Neighboring gene lectin-37Da Neighboring gene lectin-37Db Neighboring gene uncharacterized protein Neighboring gene RtcB RNA ligase Neighboring gene Rab9

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kinesin heavy chain function in Drosophila glial cells controls neuronal activity. Schmidt I, et al. J Neurosci, 2012 May 30. PMID 22649226, Free PMC Article
    2. Non-random genomic integration - an intrinsic property of retrogenes in Drosophila? Metta M, et al. BMC Evol Biol, 2010 Apr 28. PMID 20426838, Free PMC Article
    3. Participation of a galactose-specific C-type lectin in Drosophila immunity. Tanji T, et al. Biochem J, 2006 May 15. PMID 16475980, Free PMC Article
    4. A neurogenetic mechanism of experience-dependent suppression of aggression. Ishii K, et al. Sci Adv, 2022 Sep 9. PMID 36070378, Free PMC Article
    5. Genome-wide identification and comparative analysis of Cry toxin receptor families in 7 insect species with a focus on Spodoptera litura. Li Q, et al. Insect Sci, 2022 Jun. PMID 34405540

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables alkaline phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables alkaline phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    alkaline phosphatase 12
    Names
    Alp12-PA
    Alp12-PB
    Alp12-PC
    Alp12-PD
    Alp12-PE
    CG16771-PA
    CG16771-PB
    CG16771-PC
    CG16771-PD
    CG16771-PE
    NP_001188848.1
    NP_001188849.1
    NP_001260575.1
    NP_001260576.1
    NP_609963.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19424050..19429224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273647.1 → NP_001260576.1  alkaline phosphatase 12, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260576.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6R0, Q9VIW9
      Conserved Domains (1) summary
      cl23718
      Location:134 → 579
      ALP_like; alkaline phosphatases and sulfatases

    2. NM_001201920.2 → NP_001188849.1  alkaline phosphatase 12, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188849.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6R0, Q9VIW9
      Conserved Domains (1) summary
      cl23718
      Location:134 → 579
      ALP_like; alkaline phosphatases and sulfatases

    3. NM_001273646.2 → NP_001260575.1  alkaline phosphatase 12, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260575.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6R0, Q9VIW9
      Conserved Domains (1) summary
      cl23718
      Location:134 → 579
      ALP_like; alkaline phosphatases and sulfatases

    4. NM_136119.4 → NP_609963.1  alkaline phosphatase 12, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609963.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6R0, Q9VIW9
      Related
      FBpp0080745
      Conserved Domains (1) summary
      cl23718
      Location:134 → 579
      ALP_like; alkaline phosphatases and sulfatases

    5. NM_001201919.1 → NP_001188848.1  alkaline phosphatase 12, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188848.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8E6R0, Q9VIW9
      Conserved Domains (1) summary
      cl23718
      Location:134 → 579
      ALP_like; alkaline phosphatases and sulfatases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VIW9 Q9VIW9

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