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    Gr43a Gustatory receptor 43a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35655, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gr43aprovided by FlyBase
    Official Full Name
    Gustatory receptor 43aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041243
    Locus tag
    Dmel_CG1712
    See related
    AllianceGenome:FB:FBgn0041243
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    43C.1; 43C1; CG1712; Dmel\CG1712; DmGr43a; gr43a; GR43a; GR43C.1; Gr43C1
    Summary
    Enables ionotropic sweet taste receptor activity; ligand-gated monoatomic cation channel activity; and sweet taste receptor activity. Involved in several processes, including adult feeding behavior; cellular response to fructose stimulus; and sensory perception of sweet taste. Is active in plasma membrane. Is expressed in several structures, including adult sensillum; ganglia; gustatory receptor neurons; gut section; and tarsal segment 5. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Gr43a in Genome Data Viewer
    Location:
    43B2-43B2; 2-56 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (7390869..7393161, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (3278374..3280666, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Down syndrome cell adhesion molecule 1 Neighboring gene antisense RNA:CR44071 Neighboring gene costa Neighboring gene antisense RNA:CR44201 Neighboring gene DEAH-box helicase 15 Neighboring gene Glyoxalase 1 Neighboring gene uncharacterized protein Neighboring gene ELL-associated factor

    Genomic regions, transcripts, and products

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ionotropic sweet taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables ligand-gated monoatomic cation channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables sweet taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables taste receptor activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in adult feeding behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to fructose stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in chemosensory behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in male courtship behavior IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in monoatomic cation transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of appetite IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of feeding behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of sweet taste IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sensory perception of taste NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    gustatory receptor 43a
    Names
    CG1712-PA
    CG1712-PB
    CG1712-PC
    Gr43a-PA
    Gr43a-PB
    Gr43a-PC
    gustatory receptor 43C.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      7390869..7393161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078926.3NP_523650.2  gustatory receptor 43a, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523650.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V4B7, Q9V4K2
      Related
      FBpp0088086
      Conserved Domains (1) summary
      pfam08395
      Location:10423
      7tm_7; 7tm Chemosensory receptor
    2. NM_001043066.1NP_001036531.1  gustatory receptor 43a, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036531.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9G8
      Conserved Domains (1) summary
      pfam08395
      Location:10445
      7tm_7; 7tm Chemosensory receptor
    3. NM_001299229.1NP_001286158.1  gustatory receptor 43a, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286158.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4LEE5
      Conserved Domains (1) summary
      pfam08395
      Location:10449
      7tm_7; 7tm Chemosensory receptor