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    CG12780 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35834, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12780provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033301
    Locus tag
    Dmel_CG12780
    See related
    AllianceGenome:FB:FBgn0033301
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12780; GNBP-like
    Summary
    Predicted to enable carbohydrate binding activity. Involved in defense response to virus. Predicted to be located in cell surface. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12780 in Genome Data Viewer
    Location:
    44D2-44D2; 2-59 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8551859..8552290, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4439364..4439795, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Maltase A8 Neighboring gene mangetout Neighboring gene long non-coding RNA:CR44279 Neighboring gene long non-coding RNA:CR45308 Neighboring gene Cytochrome P450 6a14

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Induction of host defence responses by Drosophila C virus. Hedges LM, et al. J Gen Virol, 2008 Jun. PMID 18474566
    2. Contrasting evolutionary patterns in Drosophila immune receptors. Jiggins FM, et al. J Mol Evol, 2006 Dec. PMID 17103056, Free PMC Article
    3. Suppression of Drosophila antifungal immunity by a parasite effector via blocking GNBP3 and GNBP-like 3, the dual receptors for β-glucans. Lu M, et al. Cell Rep, 2024 Jan 23. PMID 38175756
    4. The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila. Dostert C, et al. Nat Immunol, 2005 Sep. PMID 16086017
    5. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer's disease. Garrido-Maraver J, et al. Biol Open, 2020 Jan 14. PMID 31822473, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to virus IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in detection of biotic stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cell surface ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12780-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8551859..8552290 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136544.3 → NP_610388.1  uncharacterized protein Dmel_CG12780 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610388.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0ZWY3, A0ZWY4
      Related
      FBpp0087815
      Conserved Domains (1) summary
      pfam15886
      Location:6 → 97
      CBM39; Carbohydrate binding domain (family 32)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0ZWY4 A0ZWY4

    Gene LinkOut

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