Tom7 Translocase of outer membrane 7 [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Tom7provided by FlyBase
Official Full Name: Translocase of outer membrane 7provided by FlyBase
Primary source: FLYBASE:FBgn0033357
Locus tag: Dmel_CG8226
See related: AllianceGenome:FB:FBgn0033357
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:AT23266; CG8226; Dmel\CG8226; dtom7
Summary: Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in positive regulation of protein targeting to mitochondrion; protein import into mitochondrial matrix; and protein insertion into mitochondrial outer membrane. Part of mitochondrial outer membrane translocase complex. Is active in mitochondrial outer membrane. Is expressed in several structures, including adult head; embryonic/larval garland cell; embryonic/larval salivary gland; eye disc; and larval central nervous system. Orthologous to human TOMM7 (translocase of outer mitochondrial membrane 7). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	2R	NT_033778.4 (8951595..8952242)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	2R	NT_033778.3 (4839100..4839747)

Chromosome 2R - NT_033778.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
contributes_to protein transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in positive regulation of protein targeting to mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein import into mitochondrial matrix	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein insertion into mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein targeting to mitochondrion	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrial outer membrane	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial outer membrane translocase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial outer membrane translocase complex	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial outer membrane translocase complex	IEA Inferred from Electronic Annotation more info
part_of mitochondrial outer membrane translocase complex	ISS Inferred from Sequence or Structural Similarity more info

Names: CG8226-PA; CG8226-PB; Tom7-PA; Tom7-PB; membrane 7; translocase of outer

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